摘要
目的分析连云港地区非淋菌性尿道炎患者病原体感染情况及支原体对药物的敏感性,为临床诊断及治疗提供依据。方法以免疫层析法检测沙眼衣原体抗原,以培养法检测支原体及药物敏感性,并对结果进行分析。结果144例非淋菌性尿道炎患者中共检出沙眼衣原体11例(7.64%),检出解脲支原体65例(45.14%),人型支原体19例(13.19%);支原体的药物敏感试验情况看,解脲支原体耐药率最低的药物是美满霉素(10.17%)、强力霉素(11.85%);耐药性最高的药物是氧氟沙星(66.10%)、司帕沙星(40.68%);人型支原体耐药率最低的是强力霉素(26.32%)、美满霉素(26.32%);耐药率最高的是阿奇霉素(94.75%)、氧氟沙星(89.47%)、克拉霉素(89.47%)、罗红霉素(89.47%);多重耐药情况(耐三种及以上):解脲支原体(55.93%),人型支原体(89.47%)。结论连云港地区非淋菌性尿道炎患者以支原体感染为主;支原体药物敏感试验具有重要意义;临床标本中支原体多重耐药现象应引起高度重视。
Objective To survey the pathogen in nongonoccal urethritis patients and drug resistance of ureaplasma urealytieum and mycoplasma honinis. Methods Chlamydia trachomatis antigen was detected with immunochromatogrphy while ureaplsma urealytieum and mycoplasma honinis were detected with culture and data were treated with computer. Results 11 cases of chlamydia trachomatis were detected in 144 patients（7.64% ） ,while 65 cases of ureaplasma urealyticum and 19 cases of mycoplasma honinis were detected in 144 patients（45.14% ） ;Ureaplasma urealyticus showed low drug resistance to minocycline and doxycycline, high drug resistance to ofloxacin and sparfloxacin; Mycoplasma honinis showed low drug resistance to doxycycline and minocycline, high drug resistance to azithromycin ofloxacin clarithromycin and roxithromycin;55.93% ureaplasma urealyticum and 89.47% of mycoplama honinis showed multi-resistance. Conclusion NGU patients are mainly infected by ureaplasma urealyticum. Drug sensitivity test is of great value. Multi-resistance should be paid more attentionto.
出处
《淮海医药》
CAS
2008年第6期500-501,共2页
Journal of Huaihai Medicine
关键词
非淋菌性尿道炎
沙眼衣原体
支原体
抗药性
微生物
Nongonoccal urethritis
Chlamydia trachomatis
Ureaplasma urealyticum
Drug resistance, microbial
