摘要
脲嘧啶类化合物具有显著的除草活性.设计并合成了10个未见文献报道的N-[2,4-二取代-5-(3-甲基-2,6-二氧-4-三氟甲基-1,2,3,6-四氢嘧啶-1-基)苯基]酰亚胺类化合物,其化学结构经1HNMR,IR,HPLC/MS和元素分析表征.初步生物活性测定结果表明,该类化合物具有一定的除草活性,如9a,9b,9c,9f,9g和9h在有效成分75g/hm2剂量下,茎叶处理对苘麻(Abutilon theophrasti Medic)、刺苋(Amaranthus spinosus)等双子叶杂草的抑制率达90%以上.
Uracil compounds have significant herbicidal activity. Ten N-[2,4-disubstituted-5-（3-methy-2,6- dioxo-4-trifluoromethyl-1,2,3,6-tetrahydropyrimidin-1-yl）phenyl]imides were designed and synthesized. Their structures were confirmed by ^1H NMR, IR, HPLC/MS and elemental analysis. Preliminary bioassay showed that most of title compounds had good herbicidal activity, for example, 9a, 9b, 9c, 9f, 9g and 9h exhibited more than 90% inhibition aganist dicotyledon weeds, such as Abutilon theophrasti Medic and Amaranthus spinosus at an active ingredient 75 g/hm^2 in post-emergence treatment.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2008年第8期1433-1438,共6页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.20575019)
湖南省自然科学基金(No.07JJ1003)
晓庄学院化学生物学及中药分析教育部重点实验室开放基金(No.KLCBTCMR2008-14)资助项目
