摘要
目的探讨梅毒血清固定者的免疫功能是否异常。方法对58例经规范治疗后出现血清固定的梅毒病人,检测体液和细胞免疫功能,并与60例治疗后快速血浆反应素环状卡片试验转阴的梅毒病人的检测结果相对照,比较两组之间的差异。结果梅毒血清固定者的IgM水平高于治疗后转阴者(P<0.01),补体C3、C4水平低于治疗后转阴者(P<0.01);CD4+T细胞数低于治疗后转阴者(P<0.01),CD8+T细胞数高于治疗后转阴者(P<0.01)。结论梅毒血清固定者存在免疫功能异常。
Objective To explore if immunological functions are abnormal in syphilis patients with serum-fixation. Methods Cellular and humoral immune functions of 58 patients with syphilis serum-fixation who had been given standard therapy were tested and compared with those of 60 patients whose RPR had been converted into negative. Result Serum IgM level of patients with serum-fixation was higher than that of those with negative conversion （P 0.01 ）. C3 and CA level in patients with serum-fixation was lower than in patients with negative conversion （P 〈 0.01 ）. CD4^＋ cell count in patients with serum-fixation was lower than in those with negative conversion （P 〈 0.01 ）. CD8^＋ cell count in patients with serum-fixation was higher than in those with negative conversion （P 〈 0.01）. Conclusion Immunological dysfunction may exist in patients with syphilis serum-fixation.
出处
《中国艾滋病性病》
CAS
2008年第4期385-386,共2页
Chinese Journal of Aids & STD
关键词
梅毒
血清固定
T淋巴细胞亚群
免疫功能
Syphilis
Serum-fixation
T-lymphocyte subsets
Immunological function
