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剥夺左眼和单眼学习与雏鸡脑内Jun样蛋白表达的相关性研究

EXPRESSION OF JUN-LIKE PROTEIN IN MONOVISUAL DEPRIVED CHICK FOLLOWING ONE-TRIAL PASSIVE A VOIDANCE TASKA
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摘要 利用免疫组化技术,观察并比较剥夺一侧视觉及单眼一次性味觉厌恶回避学习后Jun样蛋白在雏鸡HV和LPO的表达,结果表明正常雏鸡HV、LPOJun表达几乎没有,剥夺左眼和单眼视觉学习后均可使Jun样蛋白增高。根据阳性神经元记数结果表明:1.视剥夺2.5、4、24小时后可使Jun样蛋白的表达逐渐增高,而且它们之间的差异显著;2.剥夺左眼2小时和24小时后训练,并分别于10分钟。 The Medial Hyperstriatum Ventrale (MHV) and Lobus Parolfactorius (LPO) have been known to be the crucial part in the memory formation process in chick, the former is more important in the stability of memory, the latter is necessary for the store of long-term memory in the chick. The Jun protein derived -from c-fos proto-oncogene has been known to form a heterodimer with Fos protein, which functions as a third messenger to induce the expression of target gene. Immunohistochemical technique was used in the present study to detect and compare Jun expressed in HV and LPO of monovisual deprived chick following one-trial passive avoidance task. It was shown that the expression of Jun was scatty in the normal chick: monovisual deprived 2.5 hours, 4 hours or 24 hours induced Jun expression definitely increased in HV and LPO; monovisual deprived hours and 24 hours following one-trail passive avoidance task and memory retention test at 10 minutes and 70 minutes after learning . induced Jun expression continue to increase in HV and LPO; Jun expression in LPO was higher than that in HV.
出处 《心理学报》 CSSCI CSCD 北大核心 1997年第4期409-413,共5页 Acta Psychologica Sinica
基金 国家自然科学基金
关键词 雏鸡 Jun样蛋白 动物心理学 单眼学习 chick, Jun-like protein, Immunohistochenical, HV, LPO, one-trail passive avoidance task.
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参考文献2

  • 1张均田,中国药理学报,1995年,11卷,1期,1页
  • 2管林初,心理学报,1991年,23卷,319页

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