摘要
采用Ｓ１００蛋白免疫组化染色对６０例乳腺癌及其周围组织中的树突状细胞进行了原位观察和数量分析。结果表明：乳腺癌组织中散在分布Ｓ１００蛋白阳性的树突状细胞，而癌周及癌旁的淋巴细胞及浆细胞密集区可见树突状细胞成簇存在。树突状细胞与乳腺癌的组织类型，腋窝淋巴结转移状况及癌周淋巴细胞及浆细胞的浸润程度有关。提示树突状细胞参与的宿主抗肿瘤免疫反应随肿瘤的不同时期而不同。
The distribution and number of dendritic cells in 60 cases of breast and tissue around the tumor were investigated. The result showed that S100 protein positive dendritic cells distributed sparsely in malignant cells and formed a cluster among lymph cells and plasma cells.Such dendritic cell was related to histologic classification of breast carcinoma, metastases in lymph node and the intensity of lymphocyte and plasma cell infiltration around the carcinoma. This finding indicated that host antitumor immunoreaction that related to dendritic cells was different according to the phases of breast carcinoma.
出处
《首都医科大学学报》
CAS
1997年第4期324-326,共3页
Journal of Capital Medical University
