摘要
用放射免疫分析法（ＲＩＡ）检测３１例癌性胸水和４０例结核性胸水病人的血和胸水中β２－ＭＧ含量，发现胸水中结核组β２－ＭＧ含量（３．７１０±０．８０９ｍｇ／Ｌ），比癌性组含量（２．９２７±１．２２５ｍｇ／Ｌ）高（Ｐ＜０．０１），两组血清β２－ＭＧ含量虽较正常明显升高（Ｐ＜０．０１），但结核和癌性组间则无区别（Ｐ＞０．０５），两组β２－ＭＧ胸水／血清比值也无统计学差别；结核组胸水β２－ＭＧ含量比其血清含量高（Ｐ＜０．０１），而癌性组则无统计差别；提示同时检测血清和胸水中的β２－ＭＧ含量在结核和癌性胸腔积液的鉴别上有一定意义。
Radioimmunoassay (RIA) was applied to detect the concentrations of β2microglobulin in sera and pleural effusion from 31 patients with malignant pleural effusion and 40 patients with tuberculous pleural effusionIt was found that concentration of β2microglobulin in pleural effusion from tuberculous group (3710±0809mg/L) was significantly higher than that from cancer group(2927±1225mg/L,P<001)Although serum β2microglobulin levels in both groups were higher than those in normal control group (P<001),there was no difference between tuberculous and malignant groups(P>005)And no difference of β2microglobulin pleural effusion/serum ratio could be observed between tuberculous and malignant groupsPleural effusion β2microglobulin level was higher than serum β2microglobulin level in tuberculous group,but not in malignant groupThese data suggested that homochronous detection of β2microglobulin in pleural effusion and serum would be of help in differential diagnosis of malignant and tuberculous pleural effusion
出处
《广西医学》
CAS
1997年第6期949-951,共3页
Guangxi Medical Journal
