摘要
目的了解葛根素对冠心病患者血液流变学的影响。方法对68例冠心病患者进行葛根素治疗,葛根素400 mg加入5%葡萄糖注射液250 mL中静脉滴注,1次.d-1,共15 d,并进行治疗前后血液流变学观察。同时选取49名查体健康者进行对照研究。结果冠心病患者存在血液流变学指标异常,葛根素治疗后血液流变学各项指标有显著改善。结论血液流变学异常可促进冠心病的发生发展,葛根素治疗后可显著改善冠心病患者血液黏稠度,其疗效可靠,毒副作用小,值得推广。
Objective To determine the effect in puerarin on hemorheology of patients With coronary heart disease. Methods A total of 68 patients with coronary heart disease were treated with 0. 4 g puerarin a day for 15 days. The change of hemorheology was observed in patients before and after the treatment and in 49 controls. Results .The patients had abnormality in hemorheology, and the abnormal hemorheology had significant improvement after the treatment. Conclusion Abnormal hemorheology is an important risk factor for coronary heart disease. Puerarin can improve the abnormal hemorheology with reliable efficacy
出处
《中南药学》
CAS
2008年第4期495-496,共2页
Central South Pharmacy
关键词
葛根素
冠心病
血液流变学
puerarin
coronary heart disease
blood rheology