摘要
目的:比较抑郁症不同表现类型-单相抑郁发作和双相抑郁发作中医证候特征,为中医辨证治疗不同类型抑郁症提供依据。方法:观察符合研究标准患者共459例。按照中医辨证的原理,结合郁证的特点,编制抑郁症中医证候流行病学调查表搜集四诊资料。结果:在459例情感障碍目前为抑郁发作的患者中,344例为单相抑郁占74.9%;115例为双相抑郁,占25.1%。单相抑郁组,男性109例占31.7%,女性235例占68.3%;双相抑郁组,男性55例占47.8%,女性60例占52.2%。单相抑郁组总病期为75.6±28.7月,双相抑郁组为139.9±33.7月。单相抑郁组有诱因者为242例,占70.3%;双相抑郁组为44例,占38.3%。单相抑郁组气虚197例占57.3%、火热185例占53.8%、阴虚138例占39.2%,血瘀193例占56.1%;双相抑郁组分别为84例占73.0%、26例占22.6%、16例占13.9%,血瘀52例占45.2%。单相抑郁组涉及中医病位肝186例占54.1%,脾196例占57.0%,双相抑郁组涉及肝99例占86.1%,脾95例占82.6%。单相抑郁组肝郁气滞型12例占3.5%,肝郁脾虚型15例占4.4%,痰气郁结型17例占4.9%,气郁化火型79例占23.0%,脾虚湿盛型92例占26.7%,心脾两虚型8例占2.3%,脾肾两虚型87例占25.3%,肝肾阴虚型34例占9.9%;双相抑郁组肝郁气滞型4例占3.5%,肝郁脾虚型38例占33.0%,痰气郁结型11例占9.6%,气郁化火型9例占7.8%,脾虚湿盛型19例占16.5%,心脾两虚型11例占9.6%,脾肾两虚13例占11.3%,肝肾阴虚型10例占8.7%。上述方面比较两组有显著性差异。结论:中医流行病学资料、证候学、病位和辨证方面两者有差异。
Objective ： To compare the characteristics of TCM syndromes between unipolar depression and bipolar depression so as to provide certain evidence for the treatment of different depressions in TCM. Methods ： A total of 459 patients were interviewed with self- designed questionnaires of TCM syndromes to collect sufficient information. Results ： Among 459 patients, 344 patients suffered from unipolar depression, accounting for 74. 9 % of the total; while 115 patients suffered from bipolar depression, accounting for 25. 1%. In the group of unipolar depression, there were 109 male patients accounting for 31. 7%, and 235 female patients accounting for 68. 3%. In the group of bipolar depression, there were 55 male patients accounting for 47. 8%, and 60 female patients accounting for 52. 2%. In the group of unipolar depression, there were 197 cases of vital energy deficiency （57. 3% ）, 185 cases of fire - heat （53. 8% ）, 138 cases of Yin asthenia （39. 2% ）, and 193 cases of blood stasis （56. 1% ）. In the group of bipolar depression, there were 84 cases of vital energy deficiency （73. 0% ）, 26 cases of fire - heat （22. 6% ）, 16 cases of Yin asthenia （ 13. 9% ）, and 52 cases of blood stasis （45. 2% ）. As for TCM disease location, in the unipolar depression, there were 186 cases of liver location （54. 1% ）, and 196 cases of spleen location （ 57. 0 % ） . In the bipolar depression, there were 99 cases of liver location （ 86. 1% ）, and 95 cases of spleen location （82. 6% ）. In the group of unipolar depression, damp abundance due to spleen asthenia （92 cases, 26. 7% ）, asthenia of both spleen and kidney （87 cases, 25. 3% ）, and stagnated Qi transformed into fire （79 cases, 23. 0% ） were the top three syndromes. In the group of bipolar depression, stagnation of Liver- Qi with spleen deficiency （38 cases, 33. 0% ）, damp abundance due to spleen asthenia 119 cases, 16. 5% ）, and asthenia of both spleen and kidney （ 13 cases, 11. 3% ） were the top three syndromes. Conclusion： There were significant differences in epidemiological data of TCM, syndromes and diseases location between unipolar depression and bipolar depression.
出处
《四川中医》
北大核心
2008年第7期18-21,共4页
Journal of Sichuan of Traditional Chinese Medicine
关键词
抑郁症
单相发作
双相发作
中医证候学
流行病学调查
depression
unipolar depression
bipolar depression
syndromes of TCM
epidemiological investigation
