摘要
评价２４ｈＳＴ段压低与血压波动的关系。方法１０７例患者进行２４ｈ动态血压检测并同时记录心电图，所有患者进行心血管危险度评价。结果以有无ＳＴ段降低进行分组（ＳＴ段降低＞１ｍｍ，＞６０ｓ）。２８例发现总共１３９段ＳＴ段压低，持续时间１５３±７５ｓ，压低幅度为１．４０±０．３５ｍｍ。在ＳＴ段降低时，收缩压升高１１±３ｍｍＨｇ，舒张压升高９±４ｍｍＨｇ，但ＳＴ段降低与心率快慢无明确相关。２４ｈ分布显示两个发病高峰，清晨及傍晚。平均动态血压负荷在ＳＴ段降低组高于ＳＴ段正常组，两组平均收缩压及舒张压ＳＴ段异常组高于ＳＴ段正常组（Ｐ＜０．０５），而白昼及夜间的平均血压亦为ＳＴ段异常组高于ＳＴ段正常组（Ｐ＜０．０１～０．０５）。两组间在临床特征、吸烟、饮酒等心血管危险因素方面无显著性差异，在高血压病程、血糖水平、血总胆固醇水平、左室重量指数等方面存在差异。结论高血压伴有ＳＴ段降低患者动态血压负荷高于无ＳＴ段降低患者，且两组患者在高血压病程、血糖、血脂水平、左室重量指数等方面存在差异。当ＳＴ段降低时，９２％血压伴随增高。ＳＴ段与心率的相关性还有待进一步研究。
Aim To asses the prevalence and circadian distribution of STsegment depression n related to concomitant blood pressure(BP) fluctuation.\ Methods\ 107 patients underwent ambulatory blood pressure monitoring(ABPM) and Holter electrocardiogram simultaneously.\ Results\ 28 patients had a total 139 episodes of STsegment depression.\ Duration of such episodes was 153±75 seconds and amplitude was 140±035 mm.\ During ST depression episodes,systolic BP increased by 11±3 mmHg,diastolic BP by 9±4 mmHg.\ There were no clear relationship between STsegment depression and HR variation.\ Circadian distribution showed 2 peaks:on awakening and in the late afternoon.\ The mean ambulatory BP load and day or night mean blood pressure were greater in the patients with than without STsegment depression for both systolic and diatolic BP(P<005).\ Plasma glucose,Plasma total cholesterol,left ventricular mass index were also higher in patients with STsegment depression.\ No signifcant differences in clinical parameters,and cardiovascular risk factors between groups.\ Conclusion\ The ambulaory BP load was greater in the patients with than without STsegment depression in hypertension.\ During STsegment depression,the level of BP increased.
出处
《高血压杂志》
CSCD
1997年第4期294-296,共3页
Chinese Journal of Hypertension
