摘要
目的观察严重烧伤患者创面换药操作痛前、后外周血C-反应蛋白(CRP)的变化,探讨CRP可否作为烧伤创面换药操作疼痛的应激反应的监测指标。方法测定在创面换药中有明显操作疼痛的烧伤患者(n=30,A组)和在创面换药中无操作疼痛的烧伤患者(n=30,B组)在创面换药前、后CRP水平的变化,并与正常对照组(n=10,C组)进行比较。结果与C组比较,A、B2组换药前、后CRP均显著升高(P<0.01);A组换药前CRP水平较B组明显升高(P<0.01);A组换药后CRP水平较换药前升高(P<0.05),B组换药前、后CRP无明显变化(P>0.05)。结论烧伤创面换药过程中严重的操作疼痛可引起患者外周血CRP升高,CRP可作为烧伤创面换药操作疼痛以及烧伤患者伤后产生应激反应的监测指标之一。
Objective To observe the diversity of CRP in peripheral blood between pro-and post-dressing changes in the burn injured patient, exploring whether CRP can act as the monitoring index, of procedural pain,stress reaction. Methods The numers of CRP in peripheral blood on procedural pain（A group, n = 30） and procedural pain-less produced （B group, n = 30） by dressing changes were measured and compared; Carry on a comparison with normal control（C group, n=10）. Results Compared with group C,the numers of groups A and B steped up remarkably （P〈0.01） ;The numens of groups A and B changed remarkably pro-dressing changes（P〈0.01） ; the numers of group A steped up after dressing changes（P〈0.05） ,the numers of group B did not change remarkably between pro-and post-dressing changes （P〉0.05）. Conclusion The process of the dressing changes in the burn injured patient, severe procedural pain make the numers of CRP in peripheral blood step up. CRP could act as the one of stress reaction monitoring index of procedural pain produced by dressing changes in the burn injured patient and burn injured patient.
出处
《江西医学院学报》
CAS
2008年第3期46-48,共3页
Acta Academiae Medicinae Jiangxi
基金
江西省卫生厅科技计划课题(050057)
关键词
烧伤
创面换药操作痛
C-反应蛋白
应激反应
burns
procedural pain produced by dressing changes
CRP
stress reaction
