摘要
目的:探讨CK34βE12与Vimentin在前列腺增生组织中的表达及前列腺炎与前列腺增生的关系。方法:利用HE染色观察正常前列腺组织及前列腺增生组织中炎细胞的浸润情况。利用免疫组织化学方法检测CK34βE12与Vimentin在正常前列腺组织与前列腺增生组织中的表达情况。结果:正常前列腺组织中无炎细胞浸润,前列腺增生组织中炎细胞浸润的阳性率为87.2%。CK34βE12在有无炎细胞浸润的前列腺增生组织中的表达无显著性差异,而Vimentin的表达有显著性差异(P<0.05)。结论:前列腺炎症能导致前列腺增生的发病,且由炎症所造成的前列腺增生主要是间质细胞的增生。
Objective： To investigate the expression of CK34βE12 and Vimentin in benign prostatic hypertrophy （BPH） and the relation of prostatitis and BPH. Methods： Infiltration of inflammatory cell in normal prostate and BPH were observed by HE. CK34βE12 and Vimentin in BPH and normal prostate were tested by immunohistochemistry S-P method. Results： No infiltration of inflammatory cell in normal prostate but BPH were found, 87.2% showed positive expression. The expression of CK34βE12 in BPH that had inflammatory cell or not has not significant difference. But Vimentin was on the contrary （ P 〈 0.05）. Conclusion： Prostatitis could cause BPH and maily hyperplasia of stroma.
出处
《沈阳医学院学报》
2007年第2期80-82,共3页
Journal of Shenyang Medical College
基金
沈阳医学院青年基金项目(No.200318)
