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重型颅脑损伤伴失血性休克与应激性溃疡的相关性研究 被引量:1

Relation ship between severe brain injury with hemorrhagic shock and stress ulcer
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摘要 目的探讨重型颅脑损伤伴失血性休克与应激性溃疡的相互关系。方法回顾性分析2002年1月~2006年12月本院收治的326例重型颅脑损伤患者的临床资料,根据有无合并失血性休克分为两组,统计两组患者发生应激性溃疡的情况,同时测定胃液和血液的pH值,并进行统计学处理。结果326例重型颅脑损伤患者总共发生应激性溃疡79例(24.2%),其中45例为失血性休克,占失血性休克的39.8%(45/113),无休克发生时应激性溃疡发生率为15.9%,两组比较差异非常显著(P〈0.01);伤后第2天血液中的pH值差异非常显著(P〈0.01),第7天无统计学意义(P〉0.05);两组患者伤后第2天和第7天胃液中的pH值无统计学意义(P〉0.05)。结论重型颅脑损伤伴有失血性休克时更易发生应激性溃疡。 Objective To study the relationship between severe brain injury with hemorrhagic shock and stress ulcer.Methods The data of 326 patients with severe craniocerebral injury adnitled in this hospital between January 2002 and December 2006,were divided into two groups according to presence or absence of hemorrhagic shock. Stress ulcer was receded, and gastric juice and blood pH at different periods were analyzed for the two groups. Results Stress ulcer developed in 39.8 % (45/113)of patients with hemorrhagic shock and 15.9(34/213) of patients aithont hemorrhagic shock, with significant difference between the two groups ( P 〈 0.01 ). Blood pH differed significantly ( P 〈 0.01) on day 2 but not on day 7( P 〉 0.05) after injury between the two groups.There was no significant differences in gastric juice pH no days 2 and 7 after injury between the two groups (P〉0.05). Conclusions Severe craniocerebral injury associated with hemorrhagic shock is liable to develop stress ulcer.
出处 《武警医学》 CAS 2008年第7期623-625,共3页 Medical Journal of the Chinese People's Armed Police Force
关键词 重型颅脑损伤 失血性休克 应激性溃疡 Severe craniocerebral injury Hemorrhagic shock Stress ulcer
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  • 1李宝民,张纪,许百男,高岩,国爱华,程东源,周定标.神经外科监护病房治疗急性上消化道出血81例报告[J].中华创伤杂志,1993,9(1):27-28. 被引量:50
  • 2梁维邦,杨树源,王明璐.颅脑损伤后早期上消化道出血及其发生机制的初步探讨[J].中华神经外科杂志,1994,10(2):104-106. 被引量:132
  • 3于明琨,张光霁,江基尧,朱诚,卢亦成,宋洋,吴光辉,姜正武.颅脑损伤后上消化道出血的高危因素分析[J].中华创伤杂志,1996,12(6):375-377. 被引量:69
  • 4洛赛克临床治疗协作组.洛赛克治疗消化性溃疡多中心临床观察924例[J].中华消化杂志,1991,11(5):252-54.
  • 5解相礼 张光霁 张洪俊.重型颅脑损伤后急性胃粘膜损伤的实验研究[J].中华创伤杂志,1996,12(3):191-191.
  • 6Harris AG.Octreotide in the treatment of disorders of gastrointestinal tract[J].Drug Invest,1992,4(3S):1-54.
  • 7McTavish D,Buckley MM,Heel RC.Omeprazole:an updated review of its pharmacology and therapeutic use in acid-related disorders[J].Drugs,1991,42(1)∶138-170.
  • 8Chan K,Lai ECS,Tuen H,et al.Prospective double-blind placebo-controlled randomized trial on the use of ranitidine in preventing postoperative gastroduodenal complications in high-risk neurosurgical patients[J].J Neurosurg,1995,82(3):413-417.
  • 9Kawano S,Tsuji S.Role of mucosal blood flow:a conceptional review ingastric mucosal injury and protection[J].J Gastroenterol Hepatol,2000,15(S):D1-6.
  • 10Heard SO,Helsmoortel CM,Kent JC,et al.Gastric tonometry in healthy volunteers:effect of ranitidine on calculated intramural pH[J].Crit Care Med,1991,19(2):271-274.

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  • 1王建华.重型颅脑损伤早期肠内营养支持的意义[J].临床医学,2005,25(2):62-63. 被引量:4
  • 2李改峰,闫斌,理国富.重型颅脑损伤急性期的综合治疗[J].中国误诊学杂志,2005,5(14):2628-2629. 被引量:5
  • 3Lal S O, Wolf S E, Herndon D N. Growth hormone, burns and tissue healing [ J ]. Growth Horm IGF Res, 2000,10( Suppl B) :39 -43.
  • 4Marik P E,Zaloga G P. Early enteral nutrition in acutely ill patients:a systematic review[ J]. Crit Care Meal,2001, 29 (12) :2264 - 2270.
  • 5Conrad S A, Gabrielli A, Margolis B, et al. Randomized' double - blind comparison of immediate - release omeprazole oral suspeension versus intraverious eimetidine for the prevention of upper gastrointestinal bleeding in critically ill patients [ J ]. Crit Care Med, 2005,33 (4) :760 -765.
  • 6Marino LV, Kimtu E M, French S, et al. To determine the effect of metoclopramide on gastric emptying in severe head injuries: a prospective, randomized controlled clinical trial [ J ].Be J Neurosurg,2003,17 ( 1 ) :24 - 28.
  • 7颜春英,周玉兰,吴巧玲.重型颅脑损伤早期营养支持的护理[J].肠外与肠内营养,2004,11(2):125-126. 被引量:7

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