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手术前后检测IL-6的临床意义 被引量:23

Clinical Significance of Detecting Serum Levels of Interleukin-6(IL-6)Before and After Operation
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摘要 作者应用双抗体夹心 ELISA法检测了41例普外科各类手术患者手术前后的 IL-6水平变化;并观察了IL-6水平与手术类别、手术持续时间的关系,与术后发热及术后并发症的联系。结果表明手术可引起体内IL-6水平的升高,升高程度与手术创伤大小有关,异常持续升高与术后并发症有一定联系。说明手术前后检测血清IL-6水平有助于判断手术应激程度及预示术后并发症的发生。 Using sandwich ELISA method, the serum levels of IL-6 of 41 patients in surgical wards were determined before and after operations. The correlations of these determinations with the types of operations, persistence of operation time and the occurrence of fever and complications were analyzed. It was found that the course of operation would induce elevation of serum levels of IL-6, and the degree of elevation might correlate with extent of demagcs induced during operations. The persistent increase of IL-6 serum levels might he correlated of the occurrence of complications. These resucts suggest that the measurement of IL-6 scrum levels is valuable to assess the extents of operative stress and to predict for the occurrence of complications after operations.
出处 《上海免疫学杂志》 CSCD 北大核心 1997年第3期177-178,185,共3页 Shanghai Journal of Immunology
关键词 白细胞介素-6 手术创伤 免疫抑制 interleukin-6 immunosuppression operative surgery
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