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卡培他滨致手足综合征的发生规律及治疗进展 被引量:14

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摘要 手足综合征(hand—foot svndrome,HFS)在1984年由哈佛医学院英格兰戴肯尼斯医院的Jacob Lokich和Chery Moore进行了报道,当时观察到在长期反复接受5氟尿培啶(5-Fu)或脂质体阿霉素化疗的患者中有25%会发生这种特异性皮肤综合征,HFS又称为掌跖感觉丧失性红斑综合征(palmar—planter erytllmdysesthesia syndrome,PPES),临床主要表现为指/趾的热、痛、红斑性肿胀,
出处 《中日友好医院学报》 2008年第3期176-178,共3页 Journal of China-Japan Friendship Hospital
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参考文献23

  • 1Lokich JJ,Moore C.Chemotherapy-associated palmar-plantar erythrodysesthesia syndrome[J].Ann Intern Med,1984,101(6):798-799.
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二级参考文献11

  • 1[1]Blum JL, Jones SE, Buzdar AU, et al. Multicenter phase Ⅱ study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol, 1999, 17 (2):485
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  • 5[5]Lokich JJ, Moore C. Chemotherapy-associated palmar-plantar erythrodysesthesia syndrome. Ann Inter Med, 1984, 101 :798
  • 6[6]Blum JL, Jones SE, Buzdar AU, et al. Multicenter phase Ⅱ study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol, 1999, 17 (2) :485
  • 7[7]Vukelja SJ, Lombardo FA, James WD, et al. Pyridoxine for the palar-plantar erythrodysesthesia syndrome. Ann Inter Med,1989, 111:688
  • 8[8]Fabian CJ, Molina R, Slavik M, et al. Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion. Invest New Drugs, 1990, 8:57
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