摘要
阿霉素（ADM）在0．02mol／L pH7．50的NaH2PO4-Na2HPO4缓冲溶液中，用氧化铟锡（ITO）电极进行线性扫描伏安法测定，得到一良好的还原峰，其峰电位为-0．63V。峰电流与ADM浓度在1．0×10^-7～5．0×10^-6 mol／L范围内呈线性关系，检出限为5．0×10^-8 mol／L。用循环伏安法研究了体系的电化学行为及电极反应机理。实验表明，该体系属两电子还原的不可逆过程。
A sensitive reductive peak with a peak potential of -0.63 V was obtained for adriamycin by cyclic voltammetry in 0.02 mol/L NaH2PO4-Na2HPO4 （pH=7.5） buffer solution on ITO electrode. The peak current was proportional to the concentration of adriamycin over the range of 1.0×10^-7～5.0×10^-6 mol/L with a detection limit of 5. 0×10^-8 mol/L. The experimental results showed that the reduction process of adriamycin was a two-electron irreversible process.
出处
《分析科学学报》
CAS
CSCD
2008年第3期338-340,共3页
Journal of Analytical Science
基金
国家自然科学基金(No.20275007)
关键词
阿霉素
电化学行为
ITO电极
Adriamycin
Electrochemical behavior
ITO electrode
