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卡培他滨治疗晚期复发/转移性乳腺癌78例分析 被引量：5

An Analysis of Capecitabine in Treatment for 78 Cases with Advanced Recurrent or Metastatic Breast Cancer
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摘要 [目的]探讨希罗达(卡培他滨)对经蒽环类和(或)紫杉类药物治疗后复发或转移性晚期乳腺癌的临床疗效。[方法]78例乳腺癌患者给予希罗达每天2500mg/m2,分早晚2次口服,连续服用2周后休息1周为1个周期,每个患者至少进行≥2个周期治疗,CR或PR、NC患者至少4周后复查。[结果]78例患者PR18例,NC36例,PD24例,有效率23.1%。常见毒副反应为手足综合征及皮肤色素沉着、恶心、厌食、呕吐、白细胞及血小板减少,其中大多数为Ⅰ￣Ⅱ度,未发现Ⅳ度毒副反应。中位生存期10.3个月。[结论]希罗达是经蒽环类和(或)紫杉类药物治疗后复发或转移的晚期乳腺癌较好的候选药物。
作者 袁霞妹 汤婉芬 楼君
机构地区 浙江金华广福医院
出处 《中国肿瘤》 CAS 2008年第6期539-540,共2页 China Cancer
关键词 乳腺肿瘤 希罗达 药物疗法
分类号 R737.9 [医药卫生—肿瘤]
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二级参考文献10

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共引文献385

同被引文献34

  • 1薛巧俊.乳腺超声多普勒筛查疾病分析[J].慢性病学杂志,2013,13(5):394-395. 被引量：1
  • 2赵韬,刘健.中医药治疗乳腺癌的现状与展望[J].福建中医学院学报,2006,16(2):67-68. 被引量：11
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  • 6孙淑娟,任磊.卡培他滨治疗转移性乳腺癌40例临床疗效分析[J].当代医学,2008,5(141):60.
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中国肿瘤
2008年 第6期

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