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卡培他滨与表柔比星分别联合多西紫杉醇治疗转移性乳腺癌的临床疗效分析 被引量:9

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摘要 目的比较卡培他滨与表柔比星分别联合多西紫杉醇一线治疗转移性乳腺癌的临床疗效。方法将68例转移性乳腺癌患者根据治疗方案的不同分为A组及B组,A组行卡培他滨联合多西紫杉醇方案治疗,B组行表柔比星联合多西紫杉醇方案,比较两组近期疗效、半年疾病无进展率、肿瘤进展时间及毒副反应发生率。结果 A组治疗有效率、临床获益率、半年疾病无进展率均差异不显著(均P>0.05);A组中位无进展生存期显著优于B组(P<0.05),3、4级手足综合征发生率显著高于B组(P<0.05),3、4级中性粒细胞减少发生率显著低于B组(P<0.05)。结论卡培他滨联合多西紫杉醇方案治疗转移性乳腺癌较表柔比星联合多西紫杉醇方案疗效佳,延长了患者的无进展生存期,毒副反应可耐受。
出处 《健康研究》 CAS 2015年第1期79-80,共2页 Health Research
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