摘要
目的:分析2型糖尿病合并周围神经病变患者的临床特征。方法:132例2型糖尿病患者根据肌电图结果判定分为正常肌电图组(n=33)、感觉神经异常组(n=51)、感觉及运动神经异常组(n=48)3组,检测并比较3组身高、体重、收缩压(SBP)、舒张压(DBP)、血肌酐(Scr)、血尿酸(UA)、空腹血糖(FPG)、糖化血红蛋白(HbA1c)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、纤维蛋白原(FIB)等指标,并分析周围神经病变程度与各指标之间的关系。结果:感觉神经异常组及运动神经异常组年龄、病程大于正常肌电图组,差异有统计学意义(P<0.05),而感觉及运动神经异常组及感觉神经异常组2组之间差异无统计学意义(P>0.05)。感觉及运动神经异常组FIB水平高于感觉神经异常组及正常肌电图组(P<0.05),而在感觉神经异常组及正常肌电图组之间差异无统计学意义(P>0.05),各组间其它指标差异均无统计学意义(P>0.05)。结论:随着年龄、病程的增加,FIB水平的增加、血糖控制不良与糖尿病周围神经病变的发生及发展相关,积极控制以上因素可延缓糖尿病周围神经病变的发生及发展。
Objective： To analyze the clinical features of diabetic periphery neuropathy in patients with type 2 diabetes （T2DM） clinical character. Methods： According to electromyography （EMG）, 132 cases with TzDM were divided into three groups. There were 33 cases in normal EMG group,51 cases in sensus nerve abnormality group,and 48 in sensus motion abnormal EMG group clinical data ,including body height, body weight, systolic blood pressure, diastolic blood pressure, serum creatinine, blood uric acid, fasting plasma glucose, glycosylated hemoglobin, total cholesterol, triglyceride, high-density lipoprotein-cholesterol, low-density-lipoprotein-cholesterol, serum fibrinogen were recorded; and analyze with diabetic peripheral neuropathy degree together with all index relationship, body mass index were calculated. Results： Age, duration of diabetes in sensus and motion abnormality group level was higher than normal electromyogramnon group with statistical significance （P〈0. 05） ; sensus nerve abnormality group was higher than normal electromyogramnon group with statistical significance （P〈0.05）. Sensus nerve abnormality group and sensus and motion abnormality group had no statistical significance （P 〉0. 05）; Fibinogen （FIB） in sensus and motion abnormality group level was higher than normal electromyogramnon group and sensus nerve abnormality group. With statistical significance （P〈0.05） sensus nerve abnormality group and normal electromyogramnon group had no statistical significance （P 〉0.05）. Conclusions： Age, duration of diabetes to increase, FIB level variation, blood sugar improper control not well correlate with diabetic peripneral neuropathy, Positive control correlated above factors may be to delay diabetic peripneral neuropathy to occur and develop.
出处
《新疆医科大学学报》
CAS
2008年第5期515-517,520,共4页
Journal of Xinjiang Medical University
基金
新疆维吾尔自治区重点学科一期建设经费资助项目(2005-区教委-01)
