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糖尿病周围神经病变与血液流变学相关性分析 被引量:44

The Relationship of Diabetic Neuropathy and Hemorheology
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摘要 目的 :分析糖尿病周围神经病变与血液流变学的相互关系。方法 :测定 114例糖尿病患者的正中神经、尺神经、腓总神经和腓浅神经的感觉神经传导速度 (SNCV)和运动神经传导速度 (MNCV)及其血液流变学指标。结果 :SNCV异常率为 5 9.4 % ,MNCV异常率为 5 3.6 % ,(P <0 .0 1)。随病程越长 ,NCV异常率逐渐升高。NCV异常组的全血黏度及红细胞聚集指数高于NCV正常组。结论 Objective: To study the relationship between diabetic neuropathy and Hemorheology. Methods: Sensory and motor nerve conduction velocity (SNCV, MNCV) of medlian nerve, cabital nerve, common peroneal nerve and superficial peroneal nerver were measured. At same time, hemorheology was also measured in 114 diabetic patients. Results: The abnormality rate of SNCV and MNCV were 59.4%,53.6% respectively (P<0.01). Abnormality rate of NCV would increased with prolongation of duration in diabetic patient. Erythrocyte aggregation index and whole blood viscosity of abnormal NCV groups were significantly higher than those of normal NCV groups. Conclusion:It is helpful to treat the diabetic neuropathy by improving the hemorheology in clinical.
出处 《中国临床医学》 2004年第4期502-503,共2页 Chinese Journal of Clinical Medicine
关键词 糖尿病 周围神经病变 血液流变学 相关性 感觉神经传导速度 运动神经传导速度 Diabetic neuropathy Nerve conduction velocity Hemorheology
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  • 1汤晓英 杨秉贤 等.运动及感觉神经传导速度测定在糖尿病性神经病早期诊断中的价值[J].中华神经精神杂志,1982,15:78-78.
  • 2[3]King GL. Abnormalities of the vascular endothelium in diabetes.Diabetes Annu, 1993,7: 107.
  • 3[4]Verrotti A, Giuva PT, Morgese G, et al. New trends in the etiopathogenesis of diabetic peripheral neuropathy. J Child Neurol,2001,16(6) :389~394.
  • 4[5]Jensen PG, Larson JR. Management of painful diabetic neuropathy. Drugs Aging, 2001,18(10) :737~749.
  • 5[6]Cameron NE, Cotter MA. Diabetes causes an early reduction in autonomic ganglion blood flow in rats. J Diabetes Complications,2001,15(4): 198~202.

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