摘要
目的:观察采用一次性中心静脉导管胸腔闭式引流后,胸腔内局部灌注化疗联合全身化疗治疗乳腺癌大量胸腔积液的疗效。方法:在常规全身化疗的基础上,胸腔闭式引流完胸水后,通过导管在胸腔内注射博来霉素。结果:胸腔积液控制的有效率77.14%,毒副作用主要是骨髓抑制、消化道反应。结论:乳腺癌伴大量胸腔积液,常规化疗的同时,通过胸腔闭式引流管局部注射博来霉素,方法简单有效。
Objective：To observe the curative effect of bleomycin regional perfusion into thoracic cavity after thoracic close drainage, associating systematic chemotherapy in breast carcinoma patients with generous hydrothorax. Methods： On the base of conventional systematic chemotherapy, the breast carcinoma patients were administrated thoracic close drainage to eliminate hydrothorax, and then perfused bleomycin into thoracic cavity through the central venous catheter . Results： The effective ratex of hydrothorax control was 77.14%, the main side effect was myelosuppression and alimentary canal response. Conclusion： Generous hydrothorax from breast carcinoma patients could be effectively controlled by perfused bleomycin into thoracic cavity through the central venous catheter base on con- ventional systematic chemotherapy ,and the therapeusis was simple.
出处
《现代肿瘤医学》
CAS
2008年第6期975-976,共2页
Journal of Modern Oncology
关键词
乳腺肿瘤
胸腔积液
局部灌注
breast cancer
pleural fluid
thoracic cavity chemotherapy
