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不完全川崎病的早期诊治 被引量:2

Early Diagnosis and Treatment of Incomplete Kawasaki Disease
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摘要 目的研究不完全川崎病(incomplet Kawasaki disease)的发病情况及临床特点.方法对2002年1月至2007年1月住院治疗的104例川崎病(KD)病例资料做了回顾性分析.结果104例中84例(80.8%)为典型KD,20例(19.2%)为不完全KD.不完全KD平均年龄(1.26±1.34)较KD组小,差异有统计学意义(P<0.01):不完全KD具备KD诊断标准6条中的4项或3项,冠状动脉扩张和冠状动脉瘤的发生率为55.6%,与KD比较差异有统计学意义.在治疗中不完全KD对丙种球蛋白无反应的发生率高于KD.结论不完全KD多见于小年龄婴幼儿,且冠状动脉病变发生率高,冠状动脉病变是诊断不完全KD的重要依据,临床应重视早期诊断和早期治疗. Objective To study the incidence and clinical characteristics of incomplete Kawasaki disease (KD). Method The data of 104 in-patients with Kawasaki disease from January 2001 to January 2007 were retrospectively analyzed. Results 84 of 103 patients suffered from typical KD and 20 patients suffered from incomplete KD. The mean age of patients from incomplete KD was younger than that of typical KD and the difference was significant compared to that of typical KD (P 〈 0.01 ). There were 3 to 4 items among 6 items of standard diagnosis in atypical KD. Rate of incidences of coronary artery dilation (CAD) and coronary artery aneurism (CAA) in incomplete KD was 55.6% which was significantly different from that of typical KD (P 〈 0.01 ). The incidence of no response to immunoglobin in the treatment of incomplete KD is higher compared to that in KD. Conclusions The incidence rate of incomplete Kawasaki disease is higher in younger infant. The incidence rate of coronary artery dilation (CAD) is higher than that in atypical KD, so it' s an important diagnose indicator in incomplete KD.
出处 《昆明医学院学报》 2008年第2期159-161,共3页 Journal of Kunming Medical College
关键词 不完全川崎病 冠状动脉病变 诊断 Incomplete Kawasaki disease Coronary artery dilation Diagnosis
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