摘要
炎症性肠病(IBD)主要包括溃疡性结肠炎(UC)和克罗恩病(CD)两种疾病。近年我国IBD的发病率不断上升,如未及时治疗,长期炎症将最终导致结直肠癌的发生风险增高。在各种结直肠癌预防措施中,化学预防日益受到关注。本文主要对IBD合并结直肠癌的现状和发病机制作一综述,重点介绍几种用于化学预防的药物。
Inflammatory bowel disease （IBD） includes ulcerative colitis （UC） and Crohn＇s disease （CD）. The incidence of IBD has increased in China in recent years, and patients with IBD will have high risk for colorectal cancer （CRC） if not treated in time. More attention has been paid to chemoprevention of CRC. This review article introduced the present status and pathogenesis of IBD patients complicated with CRC, with focus on several agents used for chemoprevention.
出处
《胃肠病学》
2008年第5期312-314,共3页
Chinese Journal of Gastroenterology
关键词
炎性肠疾病
结直肠肿瘤
化学预防
Inflammatory Bowel Diseases
Colorectal Neoplasms
Chemoprevention
