摘要
幽门螺杆菌感染是慢性胃炎、消化性溃疡的主要病因.也是胃癌的Ⅰ类致癌原.根除幽门螺杆菌后,胃黏膜炎症得以明显改善,是否胃黏膜萎缩、肠化也能因此而逆转,并成为胃癌的化学预防手段之一?本文对现有的研究结果进行了系统评述,认为根除幽门螺杆菌感染是一种潜在的化学预防胃癌的措施,尤其对于高危人群,应检测并根除幽门螺杆菌,进行胃癌预防.
Helicobacter pylori is a major pathogen of chronic gastritis and peptic ulcers, as well as type Ⅰ carcinogenesis. Inflammation of gastric mucosa is improved after eradication of H pylori. However, does eradication of H pylori reverse atrophic gastritis and intestinal metaplasia, and therefore may it be a way to prevent gastric cancer？ This paper reviews studies of the relationship between H pylori and gastric cancer. It was concluded that eradication of H pylori is a potential method to prevent gastric cancer, and that H pylori should especially be tested for and treated in high-risk populations.
出处
《世界华人消化杂志》
CAS
北大核心
2007年第25期2669-2671,共3页
World Chinese Journal of Digestology
关键词
幽门螺杆菌
根除
胃癌
化学预防
Helicobacter pylori, Bacterial eradication
Gastric cancer
Chemoprevention
