摘要
为观察尼莫地平对创伤性蛛网膜下胜出血（t－SAH）的治疗作用，作者将45例患者随机分为常规治疗组（n＝22）和常规加尼莫地平治疗组（n＝23），所有患者均行颅内压（ICP）监护并按国际GOS预后评分标准进行疗效判定。结果预后不良者在常规治疗组中占59％，而在尼莫地平组仅占26％（P＜0．05），两组ICP变化则无显著性差异（P＞0．05）。研究结果显示，应用尼莫地平治疗t－SAN能明显降低死残率，改善预后，且对ICP无明显影响。
To observe the clinical effects of nimodipine on treatment of traumatic subarachnoid hemorrhage (t - SAH), 45patients were divided randomly into 2 groups: routine treatment grpup(n = 22) and routine plus nimodipine treatment group(n = 23). The ICP changes were monitored and GOS was used to assesed the patient's outcome. The results showed the outcome was unfavourable in 54. 5% of routine treatment patients compared to 30. 4% of nimodipine treatment patients(P < 0. 01 ), but no statishcally significant diffevence in ICP change between the two groups . The results suggst that treatmnt for t - SAH with nimodipine can significantly reduced the unfavourable outcome. but without marked influence on ICP.
出处
《广东医学》
CAS
CSCD
1997年第10期657-658,共2页
Guangdong Medical Journal
