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尼莫地平对创伤性蛛网膜下腔出血预后的影响 被引量:6

Effect of Nimodipine on Prognosis in Traumatic-subarachnoid Hemorrhage Patients
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摘要 目的研究尼莫地平在创伤性蛛网膜下腔出血的应用,及其对预后的影响。方法回顾性分析138急性颅脑损伤合并有蛛网膜下腔出血的患者,随机分为尼莫地平治疗组70例和对照组68例,观察两组脑梗死、脑积水发生情况,随访3个月进行预后判断并进行统计学分析。结果尼莫地平治疗组脑梗死、脑积水发生率明显低于对照组(P<0.05),预后较对照组好。结论在合并蛛网膜下腔出血的颅脑损伤病例,早期使用尼莫地平可降低蛛网膜下腔出血所致的脑梗死、脑积水等并发症,改善预后。 Objective To explore the effect s of nimodipine therapy and prognosis in patients with traumatic subarachnoid hemorrhage. Methods 138 patients were randomly divided into treatment group and control group. The treatment group(70 cases) received early nimodipine therapy and the control group(68 cases) was supported with common method. At the same time, the complications with cerebral infarction and hydrocephalus during treatment were observed and the prognosis were judged. All data were statistily analyse. Results The incidence rate of cerebral infarction and hydrocephalus in nimodipine treatment group was lower obviously than control group. And prognosis in treatment gruoup were better than those of control group. Conclusions It is useful that the cases of cerebral injury with traumatic subarachoid hemorrhage receive the treatment of nimodipine. The early nimodipine therapy can be beneficial to depress the occurrence of cerebral infarction and hydrocephalus and improve the prognosis.
出处 《医学研究杂志》 2007年第11期63-64,2,共3页 Journal of Medical Research
关键词 创伤性蛛网膜下腔出血 尼莫地平 预后 Traumatic subarachnoid hemorrhage Nimodipine Prognosis
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参考文献5

  • 1苏贺先,马骏,娄飞云,张先闯,张凤银.尼莫通在外伤性蛛网膜下腔出血中的应用[J].蚌埠医学院学报,2000,25(1):36-37. 被引量:3
  • 2Greene KA, Marciano FF, Johnson BA, et al. Impact of traumatic subarachnoid hemorrhage on outcome in nonpenetrating head injury (part Ⅰ) : a proposed computerized tomography grading scale. J Neurosurg,1995, 83:445 -452
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  • 5刘剑平,赵树琦,姚太俊.尼莫地平在颅脑损伤治疗中的脑保护作用[J].广东医学,2006,27(3):420-422. 被引量:21

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