摘要
本文将120例CRF病人分为两组,治疗组用肾衰口服液治疗,对照组用温脾汤治疗。结果:治疗组63例,显效率49.2％,有效率为36.5％;对照组57例,显效率33.3％,有效率35.1％。两组疗效比较,治疗组显效率和总有效率均高于对照组(P<O.05)。动物实验也表明,肾衰口服液对腺嘌呤复制的大鼠CRF有良好的治疗作用,能升高Hb和血清蛋白,对肾衰大鼠高钾、高磷、低钙血症有不同程度的改善。同时能提高肾小球的滤过率,显著降低血中BUN、Cr、β_2-MG以改善肾功能。延缓腺嘌呤致大鼠CRF的进展,减少结晶物在肾组织的沉积,减轻肾脏病理损害,对肾脏具有一定保护作用。提示肾衰口服液对CRF有较好的防治作用。
120 patients with chronic renal failure (CRF) were divided into two groups, ie, treated group treated with Shenshui oral liquor (SSOL) and control group treated with Wenpitang- Results showed that the signifcant effective rate and effective rate of treated group was 44- 2% and 36. 5% respectively and significant effective rate and effective rate of control group was 33- 3% and 35. 1% respectively. Both significant effective rate and total effective rate of treated group was higher than that of control group (P<0. 05). Experimental study showed that: SSO1 could effectively prevente and treat CRF in rats induced by adenyl. SSOL could increased Hb and serum albumin as well as improved hyperkalemia^ hyperphosphatemiaN hypocalcemia in rats with CRF. SSOL could raise CFR and decrease the content of BUN^Cr^-M. SSOL could also prevente the development of CRF, reduced the edposition in kidney tissue, relieved the degree of kidney injury. These suggested that SSOL was effective on preventing and treating CRF.
出处
《中国中医药科技》
CAS
1997年第5期264-265,共2页
Chinese Journal of Traditional Medical Science and Technology
