摘要
目的研究磁共振灌注成像技术应用于儿童大脑胶质瘤诊断的可行性及其扫描技术的优化。方法儿童大脑胶质瘤患儿18例,男12例,女6例,年龄5～16岁,对照组儿童25例,男16例,女9例,年龄3～14岁。使用GE1.5T Signa High-SpeedMRI扫描仪,双倍剂量造影剂马根维显(0.2mmol/kg)根据不同患儿血管情况分别以2～4ml/s注入速度通过18G套管针经最佳的血管注射,随后以相同速度注射生理盐水20ml。结果磁共振灌注图像质量分为"差""中""优"分为三级,造影剂注射速度2ml/s组灌注图像质量多为"差"(12/17),注射速度3ml/s组多为"中"(14/16),注射速度4ml/s组全为"优"(6/6)。结论磁共振灌注图像的质量与造影剂注射速度密切相关,造影剂注射速度>3ml/s是获得满意磁共振灌注图像的基本条件;而扫描前护士对血管的选择及血管状况的评估是造影剂高速注射成功的前提。
Objective To study the feasibility and optimization of magnetic resonance perfusion weighted imaging （MR PWI） in the diagnosis of cerebral glioma in children. Methods 18 cases with cerebral glioma were selected as the trial group （female-6. mal=12, aged from 5 to 16 years） while 25 cases without cerebral glioma were selected as the contrast group. GEl.ST Signa High-Speed MRI scanner were used and double dosage （0.2 mmol/kg） Gd-DTPA were given by 18（3 trocar through the best vein ofeach child. The injection speed ranged from 2 to 4ml/s. And then 20ml physiological saline were injected at the same speed. Results The DWI quality was divided into bad, good and best. The image quality was bad in the group in which the injection speed was 2ml/ s （12/17）, the image quality good in the group in which the injection speed was 3ml/s （14/16） and the image quality was the best in the group in which the injection speed was 3ml/s （6/6）. Conclusion The image quality was determined by the injection speed of Gd-DTPA（〉3ml/s）. Successful contrast injection depends on nurses＇ choice and evaluation of blood vessels before scanning.
出处
《中国CT和MRI杂志》
2008年第2期7-10,共4页
Chinese Journal of CT and MRI
基金
汕头市重点科技攻关项目[2005]116号
关键词
儿童
大脑胶质瘤
磁共振成像
灌注
children
cerebral glioma
magnetic resonance imaging
perfusion
