摘要
目的:观察直肠癌术中区域化疗的术中特征。方法:直肠癌术中经区域动脉灌注含5-Fu(15mg/kg)和亚甲蓝注射液2ml的化疗液,观察术中特征。结果:术中经区域动脉灌注含亚甲蓝注射液的药液后,直肠及系膜迅速变兰,并在灌注后2分钟染色最深,此后,染色逐渐消退,但全手术过程直肠仍可见染色,且盆腔渗出液明显增多。结论:直肠癌术中区域化疗可使直肠肿瘤在手术过程中暴露于化疗药物,且含高浓度化疗药物的盆腔液明显增多,对预防直肠癌术后复发具有积极作用。
Objective：To observe the characteristics of intra -operational regional ebemotherapy of rectal cancer. Methods： Patients underwent the treatment of intra - operational regional chemotherapy with the 5 - Fu（15mg/kg） and methylene blue injection. The characteristics during operation were observed. Results： After intra-operational regional ebemotberapy, rectum and mesenterium present blue quickly, thickest on 2 minutes and then drop slowly. But rectum and mesenterium present blue during whole operation, and peritoneal fluid increases. Conclusion： The intra - operational regional chemotherapy of rectal tumor enable rectal tumor to be exposed to ebemotherapeuties, increase peritoneal fluid contained drug, and has significance in preventing post - operative raeurrenee.
出处
《现代肿瘤医学》
CAS
2008年第5期800-801,共2页
Journal of Modern Oncology
关键词
直肠肿瘤
药物疗法
区域化疗
rectal cancer
chemotherapy
regional chemotherapy
