摘要
为了提高前列腺癌的治疗效果,从1989年1月至1995年5月,分别采用去势治疗和根治手术治疗前列腺癌107例和23例,观察随访2~78个月,平均315个月,随访率738%。根治术组的1、2、3、5年生存率分别为714%、667%、500%和333%,去势组则分别为679%、512%、297%和108%。两组死亡病例的生存期平均为174和260个月,但根治术组的病例生存质量较差。结果认为:根治手术提高了生存率,但一定程度降低了生存质量。主张对于A期患者,采用前列腺包膜内切除,分化差的小肿瘤及时行根治手术;B期患者,只要患者条件允许,根治最为适宜;C1期患者,预期寿命长,亦可采用根治术;C2期和D期患者仅适用去势治疗。
Radical prostatectomy has been carried out for 23 cases and castration for 107 cases of prostatic cancer. 96 patients (73.8%) have been followed up for 2~78 months with a mean of 31.5 months. The survival rate of the radical prostatectomy group has beem 71.4% at l year, 66.7% at 2 years, 50.0% at 3 years and 33.3% at 5 years.That of castration group has been 67.9% at l year,51.2% at 2 years ,29.7% at 3 years and 10.8% at 5 years. The quality of life, however, is worse in the radical prostatectomy group. The therapeutic strategy depends mainly on the clinical stage and pathological grade of the tumor. It was suggested that routine prostatectomy is suitable for stage A patients, while radical prostatectomy is indicated for B and C 1 and castration for C 2 and D stage.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1997年第4期231-233,共3页
Chinese Journal of Urology
关键词
前列腺肿瘤
癌
去势
根治术
Prostatic neoplasms Carcinoma Castration Radical operative