摘要
目的:总结手术切除加局部注射平阳霉素治疗小儿血管瘤和血管畸形的临床效果。方法:本组56例小儿血管瘤,行手术切除大部分瘤体、残余瘤体内注射平阳霉素治疗。术中将配好的平阳霉素分点注射进肿瘤组织内,注射时根据患者的年龄,血管瘤的范围决定注射剂量,一般每一点注射2ml-4ml,以瘤体轻度发白为度,一次注射总量不超过24mg。第一次注射后一期缝合创面,之后每两周注射一次。结果:32例经手术及3次注射治愈(57.14%);13例经3次注射治愈(23.21%);9例经5次注射治愈(16.07%);2例无效(3.57%),治愈率为96.4%。56例中切口感染2例,经抗感染及交换敷料治愈;注射后引起患儿发热2例,体温37.6℃-38.2℃,经对症处理缓解。未见发生药物过敏或中毒现象。患儿生长发育正常。结论:平阳霉素注射可以配合手术用于不能全部切除的小儿血管瘤和血管畸形的治疗。
Objective：To summary the clinical treatment results for children patents suffering from hemangioma by operation combined with pingyangmycin injection. Methods： Fifty - six cases of hemangioma received operation resection for the main parts of the tumor, and the remaining tumors were injected with pingyangmycin Results： Thirty one cases cured by operation combined with pingyanmycin injection 2 times, 13 cases cured by injection 3 times, and 9 cases were cured with 5 times injection,2 cases were failure. Conclusion： The pingyangmycin injection could be used for patients suffering from hemangioma which could not be totally removed by operation.
出处
《现代肿瘤医学》
CAS
2008年第4期627-628,共2页
Journal of Modern Oncology
关键词
血管瘤
手术
平阳霉素
小儿
hemangioma
operation
pingyangmycin
children
