摘要
目的:探讨成人急性白血病自然缓解的特点及其可能原因。方法:对1例成人急性混合细胞白血病的临床资料、细胞形态学、流式细胞仪免疫分型结果进行分析,并结合文献进行复习。结果:16例成人急性白血病自然缓解病例中急性淋巴细胞白血病2例,急性非淋巴细胞白血病12例,急性混合细胞白血病占1例。大多有输血和抗感染史。结论:成人白血病自然缓解病例鲜见报道,推测输血和抗感染能通过激活白血病特异的T细胞反应可能与自发缓解有关。
Objective：To increase the knowledge and understanding of spontaneous remission in adult acute leukemias. Methods：One case acute biphenotype leukemia was presented, the clinical data was analysed and related literatures were reviewed. Results： Among 16 cases of adult acute leukemias with spontaneous remission, reported by literatures ,2 were acute lymphocytic leukemias, 12 were acute myeloid leukemias and 1 was acute biphenotype leukemia. 1 case leukemia subtype was not available. Most patients had the h/story of blood transfusions and bacteria infections. Conclusion：Spontaneous remission in adult acute leukemias is rarely reported. We speculate that leukemia specific T cells might be relevant for induction of spontaneous remission during blood transfusion or bacterial infections.
出处
《现代肿瘤医学》
CAS
2008年第4期619-620,共2页
Journal of Modern Oncology
关键词
急性白血病
输血
感染
自然缓解
acute leukemia
blood transfusion
infectction
spontaneous remission
