摘要
[目的]了解烟台市孕妇风疹免疫水平,为CRS预防和风疹疫苗免疫策略制定提供依据。[方法]2005年11月至2006年1月在烟台的芝罘区、栖霞市、莱阳市的7所大型医疗机构产科就诊孕妇作为调查对象,采用酶联免疫吸附试验(ELISA)方法,检测其R-IgG抗体滴度。[结果]孕妇风疹抗体阴性率为19.32%,GMT为29.24,局部农村地区孕妇对风疹病毒易感比率高达28.36%。年龄组间差异无统计学意义(P>0.05),地区间差异有统计学意义(P<0.05)。[结论]烟台市孕妇风疹抗体水平较低,应对育龄期妇女实施选择性风疹疫苗免疫策略,并将其列入计划免疫管理之中,可以有效提高育龄期妇女风疹抗体水平,控制CRS发生。
[Objective]To understand rubella immunity level among Yantai pregnant women, provide scientific basis for CRS prevention and rubella immunization strategy. [Methods]Investigation was conducted for pregnant women visiting in 7 big hospitals from November, 2005 to January, 2006 in Zhifu, Qixia, Laiyang district of Yantai with the method of ELISA,R-IgG antibody level was tested. [Results]The negative rate of rubella antibody among pregnant women was 19.32%, GMT 29.24, compares with other provinces, the antibody level of woman of child-bearing age is lower, especially in partial countryside area,it can reach to 28.36% There was no difference in different aged group （ P〉0.05）. While there was a difference in different districts. （ P 〈0.05）. [Conclusion] Rubella antibody level among Yantai pregnant women was lower,rubella immunization should be strengthened for the target population, it must be brought into the line of programmed immunization, rubella antibody level can be improved effectively, the epidemic of CRS can be controlled.
出处
《预防医学论坛》
2008年第2期177-178,共2页
Preventive Medicine Tribune
关键词
风疹
IGG抗体
监测
Rubella
IgG Antibody
Monitoring
