摘要
为探讨缺血性中风时红细胞与正常内皮细胞的粘附特点，采用流室系统对脑血栓形成、短暂脑缺血发作患者血红细胞与正常内皮细胞粘附特性进行了研究。结果显示脑血栓形成组及短暂脑缺血发作组红细胞与正常内皮细胞粘附数量较正常组明显增加；而短暂脑缺血发作组与脑血栓形成组比较差异无显著性（Ｐ＞０．０５），提示红细胞与内皮细胞粘附作用增强可能在缺血性中风发病过程中起了重要作用。
Adherence of erythrocytes to human umbilical vein endothelial cells (HUVEC) in patients with cerebral thrombosis and transient ischemic attack(TIA) were quantitatively studied in the flow chamber system,compared with that in healthy subjects.We found:(a) The adherence of erythrocytes to HUVEC in patients with cerebral thrombosis and TIA increased,compared with that in healthy subjects;(b) The adhesion of erythrocytes to HUVEC in patients with TIA was not significantly different from that of patients with cerebral thrombosis.These suggested that the increased adhesion of erythrocytes to endothelial cells might play an important role in the pathologic process of ischemic stroke.
出处
《华西医科大学学报》
CSCD
1997年第2期193-196,共4页
Journal of West China University of Medical Sciences
基金
国家自然科学基金
关键词
脑血栓形成
短暂性脑缺血
粘附
红细胞
Cerebral thrombosis Transient ischemic attack Adherence Erythrocyte Endothelial cell
