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CTL表位多肽疫苗抗肿瘤研究进展 被引量：5

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作者 陈婷 汤旭东 万瑛 房殿春 杨仕明
机构地区 第三军医大学西南医院全军消化病研究所 第三军医大学基础部全军免疫学研究所
出处 《实用临床医药杂志》 CAS 2008年第1期38-46,共9页 Journal of Clinical Medicine in Practice
基金 国家自然科学基金资助项目(30570841)
关键词 细胞毒性T淋巴细胞(CTL) 多肽疫苗 肿瘤免疫治疗
分类号 R730.5 [医药卫生—肿瘤]
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参考文献68

  • 1Yu Z, Restlfo NP. Cancer vaccines: progress reveals new complexities[J]. J Clin lnvest, 2002, 110(3) : 289.
  • 2Heo Y S, Hwang S H Kwon O J,et al. Structural aspect of novel HLA-A *02 allele, A * 0286, identified by sequence- based typing[J]. Tissue Antigens, 2006, 67(1): 84.
  • 3van der Bruggen P, Traversari C, Chomez P, et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma [ J ]. J Immunol, 2007, 178 ( 5 ) : 2617.
  • 4Schmidt-Weber C B, Blaser K. Immunological mechanisms in specific immunotherapy [ J ]. Springer Semin Immunopathol, 2004, 25(3-4): 377.
  • 5Bhasin M, Raghava GP. A hybrid approach for predicting promiscuous MHC class I restricted T cell epitopes [J ]. J Biosci, 2007, 32(1): 31.
  • 6Rotzschke O, Falk K, Stevanovic S, et al. Exact prediction of a natural T cell epitope[J]. Eur J Immunol, 1991, 21 (11): 2891.
  • 7Rammensee H, Bachmann J, Emmerich N P, et al. SYF- PEITHI: database for MHC ligands and peptide motifs[J]. Immunogenetics, 1999, 50(3-4): 213.
  • 8Brusic V, Rudy G, Honeyman M C, et al. Prediction of MHC class II-binding peptides using an evolutionary algorithrn and artificial neural network [J ]. Bioinformatics, 1998, 14(2): 121.
  • 9Margalit H, Altuvia Y. Insights from MHC-bound peptides [J]. Novartis Found Symp, 2003, 254: 77.
  • 10Kesmir C, Nussbaum A K, Schild H, et al. Prediction of pmteasorne cleavage motifs by neural networks[J]. Protein Eng, 2002, 15(4): 287.

二级参考文献12

  • 1[1]Feller A J, Duan Z, Penson R, et al. TRAG-3, a novel cancer/testis antigen, is overexpressed in the majority of melanoma cell lines and malignant melanoma [J]. Anticancer Res, 2000, 20(6B): 4 147-4 151.
  • 2[2]Chen Z, Zhu B, Wu Y. Expression of TRAG-3 antigen in non-small-cell lung carcinomas [J]. Lung Cancer, 2002,38(1): 101-102.
  • 3[5]Rosenberg SA. Progress in human tumor immunology and immunotherapy [J]. Nature, 2001, 411(6 835): 380-384.
  • 4[7]Schirle M, Weinschenk T, Stevanovic S. Combining computer algorithms with experimental approaches permits the rapid and accurate identificaton of T cell epitopes from defined antigens [J]. J Immunol Methods, 2001, 257(1/2): 1-16.
  • 5[8]Celis E, Fikes J, Wentworth P, et al. Identification of potential CTL epitopes of tumor-associated antigen MAGE-1 for five common HLA-A alleles [J]. Mol Immunol, 1994,31(18): 1 423-1 430.
  • 6[9]van der Bruggen P, Bastin J, Gajewski T, et al. A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3 [J]. Eur J Immunol, 1994, 24(12):3 038-3 043.
  • 7[10]Parkhurst MR, Fitzgerald EB, Southwood S, et al. Identification of a shared HLA-A * 0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2) [J]. Cancer Res, 1998,58(21 ): 4 895-4 901.
  • 8U. Leonhardt,U. Ritzel,M. Ottleben,A. Vignoli,G. Ramadori. Detection of circulating albumin-mRNA by RT-PCR does not indicate metastasizing hepatocellular carcinoma[J] 1997,Langenbecks Archiv für Chirurgie(2):83～86
  • 9耿淼,贾正才,万瑛,赵建平,吴玉章.肿瘤抗原MAGE2HLAA2限制性CTL表位的预测[J].第三军医大学学报,2000,22(10):934-936. 被引量：6
  • 10贾正才,吴玉章,万瑛.肿瘤抗原MAGE-3CTL预测表位的计算机分子模拟研究[J].第三军医大学学报,2000,22(10):937-939. 被引量：4

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实用临床医药杂志
2008年 第1期

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