摘要
目的:研究肠内免疫营养对食管癌手术后病人免疫功能及蛋白质代谢的影响。方法:将42例食管癌病人随机分为肠内免疫营养组(研究组)和常规肠内营养组(对照组),分别于术后第2～8天给予等氮、等热量的肠内营养支持。于手术前1天、术后第1天和第9天分别检测IgG、IgM、IgA、总淋巴细胞数,用药期间留24h尿计量,用自动生化仪检测24h尿中尿素和肌苷排泄量。结果:研究组IgA、总淋巴细胞数均显著高于对照组,24h尿尿素和肌苷排泄量显著低于对照组。结论:肠内免疫营养可提高食管癌术后病人免疫力,改善机体蛋白质代谢功能。
Objective： To evaluate the role of postoperative enteral immunonutrition in host immunal status and changes of protein metabolisom. Methods.forty two patients with oesophageal carcinoma were randomized to receive either an immune enhancing enteral diet or an isocaloric,isonitrogenous control diet for 9 days. Enteral feeding was initiated 24 hours after surgery. The parameters of the immune function were measured before operation and at the postoperative intervals. At the same time,the urea and creatine excretion in urine was examed. Results ：The IgA level and total lymphocyte counts were significantly higher in the study group than those in the control group. The excretion of urea and creatine was significantly lower in study group compared with＂ the control .group. Conclusion. The postoperative administration of immunonutrition in patients with oesophageal carcinoma can positively modulate postoperative immunity and improve the function of protein metabolisom.
出处
《黑龙江医药科学》
2008年第1期33-34,共2页
Heilongjiang Medicine and Pharmacy
关键词
肠内营养
免疫
蛋白质代谢
enteral nutrition
immune
protein metabolisom
