摘要
目的 探讨高分辨率超声产前检测胎儿胸腺大小的方法，建立正常胎儿胸腺大小的参考值范围。方法 对347例正常胎儿（20～38孕周），在胎胸横断面“三血管”或“三血管气管”切面测量胸腺周长，计算不同孕周胸腺周长的均数及90％可信区间，胸腺周长与孕周（GA）的关系采用线性回归分析。结果 成功测量320例正常胎儿的胸腺，胸腺周长随孕周的增加而增加，直线回归方程为：胸腺周长：-4．107＋0．441×GA。结论 应用高分辨率超声可清楚观察20～38孕周胎儿的胸腺，正常胎儿胸腺大小参考值范围可进一步应用于产前诊断各种胸腺的病理情况或成为发现其他胎儿畸形的线索。
Objective To investigate the method of detecting fetal thymus by high resolution ultrasound and to establish a nomogram for fetal thymus size during 20-38 weeks of gestation. Methods Three hundred and forty seven normal fetuses were studied. Thymus sizes were obtained in the transverse section of the fetal chest （the “threee-vessel” or “threee-vessel-trachea” view）. The predicted mean and 90% reference range of thymus perimeter at each gestational age（GA） were calculated. Linear regression of thymus size on GA was calculated. Results Adequate thymus size measurements were obtained in 320 fetuses. The thymus perimeters increased with increasing GA. Thymus size as a function of GA was expressed by the regression equation： thymus size = - 4. 107 ＋ 0.441 × GA. Conclusions Asessment of thymus sizes during 20～38 weeks of gestation is feasible using high resolution ultrasound. Reference value ranges of thymus perimeter had been established in this study, and they may be helpful in the prenatal diagnosis of thymic pathologies.
出处
《中华超声影像学杂志》
CSCD
2008年第2期153-155,共3页
Chinese Journal of Ultrasonography
关键词
超声检查
产前
胸腺
Uhrasonography prenatal Thymus gland
