摘要
目的探讨产前二维及三维超声评估胎儿胸腺的最佳指标。方法对360胎孕22~39周正常单胎胎儿,应用二维超声检测胎儿胸腺的横径、前后径、周长、面积,三维超声检测胎儿胸腺体积。采用线性回归分析各测量指标与孕周的关系。并采用Steiger's t检验比较各指标与孕周的相关性。结果胎儿胸腺的横径、前后径、周长、面积及体积均随孕周的增加而增大,与孕周均呈线性相关。回归方程为:横径(cm)=-1.98+0.16×孕周;前后径(cm)=-0.80+0.08×孕周;周长(cm)=-5.00+0.42×孕周;面积(cm2)=-1.49+0.35×孕周;体积(ml)=-2.12+0.45×孕周(P均<0.01)。Steiger's t检验显示,三维超声检测胎儿胸腺体积与孕周的相关性明显优于其他指标(P<0.01)。结论对孕22~39周正常胎儿,采用三维超声测量胎儿胸腺体积是评估胸腺发育情况的最佳指标。
Objective To evaluate the best indicator for detecting normal fetal thymus using prenatal two-dimensional （2D） and three-dimensional （3D） ultrasound. Methods During 22-39 weeks of gestational ages, the 2D and 3D ultrasound measurement of thymus were performed on a total of 360 normal singleton fetuses. The transverse diameter, anterior-posterior diameter, perimeter and area of fetal thymus were detected by 2D ultrasound. The volume of fetal thymus were obtained by 3D ultrasound. Regression analysis was used to explore the relationship between gestational age and different measurement indicators. And the Steiger＇s t text was done to compare the correlations. Results The transverse diameter, anterior-posterior diameter, perimeter, area and volume of fetal thymus increased with gestational age in linear fashion. The best equations of regression were as follows：Transverse diameter （cm）=-1.98＋0.16×gestational age （week）, antero posterior diameter （cm）=-0.80＋0.08×gestational age （week）, perimeter （cm）=-5.00＋0.42×gestational age （week）, area （cm^2）=-1.49＋0.35×gestational age （week）, volume （ml）=-2.12＋0.45×gestational age （week） （all P〈0.01）. The Steiger＇s t test showed that the correlation between gestational age and thymus volume was higher than other indicators （P〈0.01）. Conclusion For normal fetuses of 22-39 gestational weeks, 3D ultrasound measurement of fetal thymus volume is the best indicator to evaluate the developmental state of thymus.
作者
王咏梅
吴云
曹荔
查文
WANG Yongmei WU Yun CAO Li ZHA Wen(Department of Ultrasound, Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China)
出处
《中国介入影像与治疗学》
CSCD
北大核心
2017年第1期31-34,共4页
Chinese Journal of Interventional Imaging and Therapy
关键词
超声检查
产前
胸腺
胎儿
Ultrasonography, prenatal
Thymus gland
Fetus
