摘要
救必应正丁醇提取物对不同状态下血压及心率作用研究结果表明,静脉注射本品对正常大鼠及夹闭颈总动脉升压大鼠均有显著降压作用,血压下降百分率尤以后者更为明显,持续时间更为长,且有减慢心率的作用。而对失血性低血压大鼠无明显影响,十二指肠灌注本品亦可使血压显著下降,而对心率无明显影响。提示本品具有明显降压和升压状态下减慢心率的作用。
It was studied that effects of n-butanol extract from Cortex Ilicis Rotundae on blood pressure and heart rate in differedt state. Results showed that the drug elicited a sgnificant depressor effect on both normal pressure and artery pressure to rise for common carotid artery blocked in rats. Of the two latter decline of percent of blood presure and active time and slowing heart rate were more significan than the former. It was same depressor effect that injected the drug into duodenum but not act to hypotensive rats. These results suggested that the drug induce significantly depressor effect and slow heart rat with the exception of hypotension.
出处
《中药材》
CAS
CSCD
1997年第8期406-408,共3页
Journal of Chinese Medicinal Materials
关键词
救必应
正丁醇提取物
血压
心率
Cortex Ilicis Rotundae
n-Butanol extract
Blood Pressure
Heart rate
