摘要
目的探讨脑胶质瘤患者生存期的相关因素。方法对资料完整的109例脑胶质瘤患者进行观察和分析，对可能影响脑胶质瘤生存期的因素采用Kaplan—Meier法和Cox回归分析进行统计学验证。结果Kaplan-Meier法单因素分析显示年龄、部位、术前患者身体机能状况评分（KPS）、病理级别、瘤周水肿、肿瘤囊变、手术方式、术后放疗八个因素对患者生存时间产生显著影响：Cox回归多因素分析显示年龄、部位、术前KPS、病理级别、手术方式、术后放疗六个因素是决定患者生存时间的主要预后因素。结论结合预后影响因素，注意治疗中的各环节，合理安排治疗模式．将有助于改善脑胶质瘤患者的预后。
Objective To evaluate the factors related to survival in brain glioma patients. Methods 109 evaluable brain glioma patients were observed and analyzed. Kaplan-Meier and Cox regression model were used to evaluate the possible prognostic factors related to long-term survival in brain glioma patients. Results In analysis of Kaplan-Meier, the following factors had a significant influence on the survival time： age, position of tumor, kamofsky performance scale （KPS） scores before operation, pathological grade, peripheral edema, cystic changes of tumor, type of surgery, and postoperative radiotherapy. In multivariate analysis of Cox regression model, the following factors had a significant influence on the survival time： age, position of tumor, KPS scores before operation, pathological grade, type of surgery, and postoperative radiotherapy. Conclusion Paying attention to the details during treatment and making suitable therapeutic strategies based on the above factors will be able to elevate the long-term survival rate of brain glioma patients.
出处
《中华神经医学杂志》
CAS
CSCD
2008年第2期157-159,共3页
Chinese Journal of Neuromedicine
关键词
神经胶质瘤
无病生存
相关因素
Glioma
Disease-free surrival
Correlation factor
