期刊文献+

人工假体置换在膝关节周围恶性骨肿瘤中的临床应用 被引量:3

Application of prosthesis replacement in limb salvage treatment of tumors in knee joint
暂未订购
导出
摘要 目的探讨人工假体在膝关节周围恶性骨肿瘤保肢术中的临床应用效果。方法膝关节周围骨肿瘤患者22例。对化疗敏感的,由肿瘤内科行正规静脉化疗,术前72小时内常规行血管造影及瘤体动脉栓塞,行骨肿瘤广泛切除或根治性切除后,采用人工膝关节假体置换重建。结果22例患者术后随访12-60个月,其中17例患者无局部复发或远处转移,4例出现复发。膝关节活动0°-110°,根据Insall评分标准治疗后效果优15例,良3例,可4例,优良率85%。结论人工假体是一种治疗膝关节周围恶性骨肿瘤较好的保肢方法,能降低局部并发症及提高临床疗效。 Objective To discuss the elinieal effects of limb salvage with artificial prosthetic knee replacement for primary malignant tumors around the knee, Methods Limb salvage surgery with prosthetic knee replacement were performed in 22 patients with malignant bone tumors around the knee including 13 cases in distal femoral 7 cases in proximal tibia and 2 cases in proximal fibula. The reconstruction of linlh function was total knee replacement with individualized prosthesis, while neoadjuvant chemotherapy was used in treating the osteosarcoma. Results 22 patients were followed up for 12 -60 months. There was no local recurrence and metastasis in 17 patients, though there were recurred in 4 patients. The extension and flexion spheres of knee activity were 0° - 110°.The functions were assessed by Insall system. The results were: 3 cases good and 15 cases excellent. The excellent rates were 85%. Conclusion It is an effective method for the treatment of malignant tumors around the knee by using rosthetie knee replacement, which can reduce the rate of local complication and improve clinical outcome.
出处 《宁夏医学杂志》 CAS 2008年第2期138-139,共2页 Ningxia Medical Journal
关键词 骨肿瘤 膝关节 假体 置换 Bone tumor Replacement Knee joint Prosthesis
  • 相关文献

参考文献8

  • 1孟淑萍,刘娜嘉.磁共振弥散加权与灌注成像技术在脑膜瘤诊断中的应用[J].宁夏医学杂志,2007,29(2):183-185. 被引量:1
  • 2Insall JN, Dorr LD, Scott RD, Rational of the knee society clinical rating system[ J]. Clin Orthop, 1989,248 : 13 - 14.
  • 3叶澄宇,杨胜武,滕红林,陈雷,林垂聪,金广健.人工假体在膝关节周围骨肿瘤保肢治疗中的应用[J].中国骨伤,2004,17(3):151-153. 被引量:3
  • 4Wunder JS, Leitch K, Griffin AM, et al. Comparison of two methods of reconstruction for primarymalignant tumors at the knee : a sequential cohort study[J], Surg Onco,2001,77 :89 -99.
  • 5Enneking WF, DunhamW, Gebhardt MC. A system for the functional evaluation of reconstructive procedure after surgical treatment of tumors of the musouloskeletal system [ J]. Clin Orthop, 1993,286 : 241 - 246,
  • 6Jeon DG,KawaiA, Boland P, et al. Algorithm for the surgical treatment of malignant lesions of the proximal tibia [ J ]. Clin Orthop, 1999, 358 : 15 - 26.
  • 7Scully SP, Ghea MA, Zurakowski D, et al. Pathologic fracture in osteosarcoma prognostic importance and treatment implieations [ J ]. Bone Joint Surg Am,2002,84:49 - 57.
  • 8吴兴,陈峥嵘,程飚,张光健.骨肉瘤治疗中化疗的作用[J].复旦学报(医学版),2003,30(5):505-507. 被引量:5

二级参考文献16

  • 1Law M,Zagzag D,Golfinos JG,Knopp EA,Johnson G.Dynamic Contrast-Enhanced Perfusion MR Imaging Measurements of Endothelial Permeability: Differentiation between Atypical and Typical Meningiomas[J].中国神经肿瘤杂志,2003,1(3):149-149. 被引量:10
  • 2夏贤良,杨迪生,范顺武,陈其昕.骨肉瘤的治疗──117例回顾[J].中华骨科杂志,1994,14(2):79-82. 被引量:14
  • 3[1]Enneking WF,Dunham W,Gebhardt MC,et al.A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system.Clin Orthop,1993,286:241-246.
  • 4[2]Wunder JS,Leitch K,Griffin AM,et al.Comparison of two methods of reconstruction for primary malignant tumors at the knee:a sequential cohort study.J Surg Oncol,2001,77:89-99.
  • 5[3]Muschler GF,Ihara K,Lane JM,et al.A custom distal femoral prosthesis for reconstruction of large defects following wide excision for sarcoma.Orthopaedics,1995,18:527-538.
  • 6[4]Kawai A,Mushler GF,Lane JM,et al.Prosthetic knee replacement after resection of a malignant tumor of the distal part of the femur.J Bone Joint Surg(Am),1998,80:636-647.
  • 7[5]Grimer RJ,Carter SR,Tillman RM,et al.Endoprosthetic replacement of the proximal tibia.J Bone Joint Surg(Br),1999,81:488-494.
  • 8Ham SJ, Schraffordt Koopsh, Vander Graaf WT, et al. Historical current and future aspects of osteosarcoma treatment. Eur J Surg Oncol,1998,24(6) :584.
  • 9Bacci G, Picci P, Ruggieri P, et al. Primary chemotherapy and delayed surgery(neoadjuvant chemotherapy)for osteosarcoma of the extremities.The istituto Rizzoli experience in 127 patients treated preoperatively with intravenous methotrexate(high versus moderate doses)and intraarterial cisplatin.Cancer,1990,65:2539
  • 10Piccip , Ferrari S,Bacci G, et al. Treatment recommendations for osteosarcomas. Drug, 1994,47 : 82.

共引文献6

同被引文献34

引证文献3

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部