摘要
室温下,以质量分数为0.2%的2-羟基-甲基苯基丙烷-1-酮(1173)为引发剂,0.5%的二乙二醇甲基丙烯酸酯(EGDMA)为交联剂,在紫外光照下合成了甲基丙烯酸2-羟基乙酯(HEMA)-N-乙烯吡咯烷酮(NVP)二元共聚物水凝胶.探讨了共聚物表面的润湿性、脱水性及对牛血清蛋白(BSA)的吸附性.试验表明,材料薄膜表面接触角随着NVP含量增大及接触时间的延长而减小;BSA通过物理作用吸附于水凝胶薄膜表面,BSA吸附量随时间延长及吸附液初始浓度升高而增大;随着共聚物中NVP含量的增大,BSA吸附量增大,而释放量减小;脱水试验表明水凝胶薄膜的脱水速率随NVP及交联剂含量的增大而减小.
Using 0.2 % 2-hydroxy-2,2dimethyl acetophenone （1173） as photo-initiator and 0.5 % ethylene glycol dimethacrylate （EGDMA）as cross-linker, HEMA-NVP copolymer hydro-gel is synthesized under UV lamp at room temperature. Copolymer surface performances including surface wetting contact angle （CA）, dehydration and adsorption on blood serum albumin （BSA） are investigated. The test result reveals that hydrogel film surface CA minish as NVP content ＆ contact time increase. BSA is absorbed on the hydrogel film surface by physical absorption. The BSA absorption amount increases as absorption time ＆ BSA initial solution concentration increase. As the NVP content increase, BSA absorption amount increases and the release amount decreases. The dehydration test shows that the dehydration rate of hydrogel decreases as NVP ＆ cross-linker content increase.
出处
《膜科学与技术》
CAS
CSCD
北大核心
2008年第1期50-54,共5页
Membrane Science and Technology
