摘要
【目的】评价外周中心静脉导管（PICC）置管引流并注入药物顺铂扣（或）阿霉素治疗恶性胸腹水的疗效。【方法】应用PICC置管对97例恶性胸腹水患者于胸腹腔作持续引流并注入药物（顺铂40～60mg，1次／周，1～2周为一周期；加用或单独利用阿霉素60mg，1次／周）治疗。【结果】97例患者恶性胸腹水的控制率为83．5％，胸腹腔注入药物后出现发热（2％）、恶心（5％）、呕吐（8％）及胸腹痛（10％）等不良反应的发生率较低，经对症处理后均能有效缓解。【结论】PICC置管引流彻底且药物顺铂或（和）阿霉素注入治疗恶性胸腹水具有方便、安全、有效、毒副作用低等优点，值得临床推广应用。
[Objective] To evaluate the efficacy of continuous drainage with peripherally inserted central catheter （PICC） combined with drug（cisplatin or/and adriamycin） infusion on malignant pleural and ascitic fluid. [Methods] Ninety seven cases with malignant pleural and ascitic fluid received continuous drainage with PICC following drug infusion ,i. e. cisplatin 40-60mg once a week for 1-2 week, plus or single adriamycin 60rng once a week. [Results] The response rate was 83. 9%. The side effects such as nausea, vomit, fever, chest pain and abdominal pain could be relieved by symptomatic treatment. [Conclusion]Continuous drainage with PICC following drug infusion is safe, effective, small adverse reaction for treating malignant pleural and ascitic fluid.
出处
《医学临床研究》
CAS
2008年第1期67-68,共2页
Journal of Clinical Research
