7[7]Kashiwakura Y,Cho HC,Barth AS,et al.Gene transfer of a synthetic pacemaker channel into the heart:a novel strategy for biological pacing[J].Circulation,2006,114(16):1682-1686.
8[8]Tse HF,Xue T,Lau CP,et al.Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN channel reduces the dependence on electronic pacemaker in a sick sinus syndrome model[J].Circulation,2006,114(10):1000-1011.
9[9]Bucchi A,Plotnikov AN,Shlapakova I,et al.Wild-type and mutant HCN channels in a tandem biological-electronic cardiac pacemaker[J].Circulation,2006,114(10):992-999.
10[10]Potapova I,Plotnikov A,Lu Z,et al.Human mesenchymal stem cells as a gene delivery system to create cardiac pacemakers[J].Cire Res,2004,94(7):952-959.
二级参考文献15
1Ludwig A,Zong X,Jeglitsch M,et al.A family of hyperpolarization-activated mammalian cation channels[J].Nature,1998,393:587
2Ludwig A,Zong X,Stieber J,et al.Two pacemaker channels from human heart with profoundly different activation kinetics[J].EMBO J,1999,18:2 323
3Ishii T,Takano M,Xie L,et al.Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node[J].J Biol Chem,1999,274:12 835
4Martin B,Angela S,Christian W.Cardiac HCN channels,structure,function,and modulation[J].Trends in Cardiovascular Medicine,2002,12(5):206
5Shi W,Wymore R,Yu H,et al.Distribution and prevalence of hyperpolarizationactivated cation channel (HCN) mRNA expression in cardiac tissues[J].Circ Res,2002,85:2e1
6Yanagihara K,Irisawa H.Inward current activated during hyperpolarization in the rabbit sinoatrial node cell[J].Pflugers Arch,2003,385:11
7Stieber J,Herrmann S,Feil S,et al.The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart[J].Proc Natl Acad Sci USA,2003,100(25):15 235
