摘要
目的:探讨布地奈德混悬液——普米克令舒雾化吸入能否促进慢性鼻-鼻窦炎行鼻内镜手术后术腔上皮化。方法:60例慢性鼻-鼻窦炎患者随机分为治疗组(30例)和对照组(30例),采用2种不同的给药方法,从术后第2周始,治疗组用布地奈德混悬液——普米克令舒2ml(1mg),接氧气动力泵进行术侧鼻腔、鼻窦的雾化吸入治疗,每天1次,连续3周;对照组用布地奈德鼻喷雾剂——雷诺考特喷鼻,每天1次。2组患者除上述给药方式不同外,其他的围术期常规治疗均相同。鼻内镜下观察并记录每例患者术腔上皮化的时间。结果:治疗组术腔平均上皮化时间为(5.3333±0.9942)周,对照组术腔平均上皮化时间为(6.6667±1.3476)周,2组比较差异有统计学意义。结论:普米克令舒接氧气动力泵,进行术侧鼻腔、鼻窦的雾化吸入治疗,有明显促进术腔上皮化和缩短疗程的作用。
Objective. Whether inhalation of pulmitcort into the sinus of chronic rhinosinusitis patients could improve reepithelization after endoscopic sinus surgery was assessed. Method： Prospective study 60 patients with chronic rhinosinusitis after endoscopic sinus surgery were divided into 2 groups randomized, the one was treatment group, and the other was control group. The patients in treatment group received inhalation of pulmitcort 2 ml plus 0.5%Aeuromycin solution 10 ml by oxygen driving force, once a day, persisting for 3 weeks, The patients in control group received Rhinocort. Besides the different therapies above mentioned above therapy was different, two groups received the same conventionalroute therapy. To observe the time of reepithelization under nasal endoscope, was observed, respectively, Result： The average time of reepithelization in treatment group was （5. 333 3 ± 0. 994 2） weeks. The other group was （6. 666 7 ± 1. 347 6） weeks, the statistical difference between the two groups was very significant. Conclusion： Inhalation of pulmitcort into the sinus can promote reepithelization and shorten the time of treatment.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2007年第23期1072-1074,共3页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
