摘要
目的分析乳腺癌脏器转移的危险因素。方法统计收治的根治和(或)改良根治术后、经正规放化疗后出现脏器转移的29例乳腺癌住院患者临床病理数据及免疫组化结果,并与同期收治、治疗方案相同且无复发转移的28例乳腺癌患者相比较,分析影响乳腺癌患者脏器转移的高危因素。结果本组出现转移的平均时间23个月,65%的患者于术后3年内出现远处转移;与对照组比较,年龄、病程、月经状况、肿瘤大小、ER、PR、Cerb-B-2之间无显著性差异,淋巴结转移及相应转移数目均较对照组多(P<0.05),初诊时肿瘤分期较对照组晚(P<0.05)。结论对于肿瘤分期较晚、淋巴结阳性、ER、PR阴性、Cerb-B-2阳性的患者,术后均应进行系统的辅助治疗,治疗完成后应定期复查。
Objective To investigate the risk factors in breast cancer patients with organ involvements. Methods Twenty- nine breast cancer patients with organ metastases were included in this study. We evaluated clinical and pathologic data and immunohistochemical outcome from breast cancer patients with organ metastases. Results The average time of organ metastases was 23 months in breast cancer patients. There were no significant difference between two groups in age, course, menstrual status, tumor size, ER, PR and Cerb - B - 2. However, lymph node involvements were more than that in control group and clinical stage was later than that in control group. Conclusion System adjuvant therapy should be advised to patients with later clinic stage, lymph node involvement, ER （ - ） , PR （ - ） and Cerb - B - 2 （ ＋ ）. Regular follow - up should be done after treatment.
出处
《宁夏医学杂志》
CAS
2008年第1期19-21,共3页
Ningxia Medical Journal
关键词
乳腺癌
脏器转移
高危因素
Breast cancer
Organ metastases
Risk factor
