期刊文献+

孕妇患牙周炎与妊娠的关系

暂未订购
导出
摘要 目的通过比较先兆早产(TPL)孕妇与健康孕妇的牙周状况,对牙周病变程度、血清肿瘤坏死因子а(TNF-а)水平与早产间的关系作初步探讨。方法收集TPL孕妇40例(TPL组),同期做定期产前检查无产兆的健康孕妇40例(对照组)。TPL组中26例足月产(TPL-TB),14例早产(TPL-PB);对照组均足月产。检查记录菌斑指数(PLI)、探诊深度(PD)、临床附着丧失(CAL)和出血指数(BI),并计算牙周炎位点(PD>3mm,CAL≥2am)率。ELISA法检测血清TNF-а。结果TPL组的PLI(0.944~0.05)、牙周炎位点率(2.93%)和血清TNF-а水平(14.81ns/L]),均明显高于对照组的(0.59±0.03)、1.32%和11.47ng/L,P<0.001。TPL-PB组的PLI(0.96±0.06)、BI(2.994~0.14)、牙周炎位点率(3.61%)和TNF-а水平(18.35ng/L)显著高于TPL-TB组的(0.66±0.04)、(2.764~0.12)、2.25%和13.70ng/L。分娩孕周和牙周炎位点率、TNF-а水平呈显著负相关(P<0.05),TNF-of水平与牙周炎位点率呈显著正相关(P<0.05)。结论牙周感染可能是早产的原因之一。
出处 《医药论坛杂志》 2007年第23期58-59,共2页 Journal of Medical Forum
  • 相关文献

参考文献7

  • 1戴钟英.早产.见:曹泽毅,主编.中华妇产科学[M].北京:人民卫生出版社,2003:333-340
  • 2李晓军,沙月琴,贺晶.母体牙周炎与早产低体重儿关系的研究进展[J].中华口腔医学杂志,2004,39(4):341-343. 被引量:20
  • 3曹采方.慢性牙周炎.见:曹采方,主编.临床牙周病学.北京:北京大学医学出版社,2006.160-185.
  • 4Offenbacher S,Jared HL,O'Reilly PG,et al.Potential pathogenic mechanisms of periodontitis associated pregnancy complications[J].Ann Periodontol,2001,3(1):233-250
  • 5Mitchell-Lewis D,Engebretson SP,Chen J,et al.Periodontal infections and pre-term birth:early findings from a cohort of young minority women in New York[J].Eur J Oral Sci,2001,109(1):34-39
  • 6Davenport ES,Williams CE,Sterne JA,et al.Maternal periodontal disease and preterm low birthweight:case -control study[J].J Dent Res,2002,81(5):313-318
  • 7刘荣坤,曹采方,孟焕新,高岩.TNF-α及IL-1β与多形核白细胞在牙周炎症组织中浸润的关系[J].中华口腔医学杂志,2000,35(5):327-329. 被引量:52

二级参考文献23

  • 1Jeffcoat MK, Geurs NC, Reddy MS, et al. Current evidence regarding periodontal disease as a risk factor in preterm birth. AnnPeriodontol, 2001,6:183-188.
  • 2Offenbacher S, Lieff S, Boggess KA, et al. Maternal periodontitisand prematurity. Part I: Obstetric outcome of prematurity and growth restriction. Ann Periodontol, 2001,6: 164-174.
  • 3Gibbs RS. The relationship between infections and adverse pregnancy outcomes: an overview. Ann Periodontol, 2001, 6: 153-163.
  • 4Li X, Kolltveit KM, Tronstad L, et al. Systemic diseases caused byoral infection. Clin Microbiol Rev, 2000, 13: 547-558.
  • 5Collins JG, Smith MA, Arnold RR, et al. Effects of Escherichia coli and Porphyromonas gingivalis lipopolysaccharide on pregnancyoutcome in the golden hamsters. Infet Immun,1994,62: 4652-4655.
  • 6Dixon NG, Ebright D, Defrancesco MA, et al. Orogenital contact: a cause of chorioamnionitis?0bstet Gynecol, 1994, 84: 654-655.
  • 7Mitchell-Lewis D, Engebretson SP, Chen J, et al. Periodontal infections and pre-term birth: early findings from a cohort of young minority women in New York. Eur J Oral Sci , 2001, 109: 34-39.
  • 8Madianos PN, Lieff S, Murtha AP, et al. Maternal periodontitis and prematurity. Part Ⅱ: Maternal infection and fetal exposure. AnnPeriodontol, 2001, 6: 175-182.
  • 9Dasanayake AP, Boyd D, Madianos P, et al. Periodontal pathogen specific maternal serum immunoglobulin level may predict low birth weight. J Dent Res, 2001, 80:188.
  • 10Offenbacher S, Jared HL, O'Reilly PG, et al. Potential pathogenic mechanisms of periodontitis associated pregnancy complications. Ann Periodontol, 1998, 3: 233-250.

共引文献69

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部