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促黄体素释放激素类似物治疗异常子宫出血

TREATMENT OF ABNORMAL UTERINE BLEEDING WITH LHRH-A
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摘要 目的:探讨国产促黄体素释放激素类似物(LHRH-A)治疗异常子宫出血的效果。方法:14例异常子宫出血患者,LHRH-A500μg/d,皮下注射3个月。用放免法测定血清PRL、FSH、LH、E2、P和T。结果:治疗后3例急性大出血者加用一般止血药,5天内出血停止,继之闭经。7例不规则出血者变为规律的周期性出血或闭经。4例有月经周期但出血量多者,出血明显减少或闭经。8例合并贫血,很快纠正。血清FSH、LH、E2和P受抑制。结论:LHRH-A治疗异常子宫出血的效果好.副作用小,无肝损害。 Objective: To investigate the effect of LHRH-A in treatment of abnormal uterine bleeding.Methods: 14 women suffering from abnormal uterine bleeding were treated with LHRH-A, 5OO μg/day, for 3months. The serum PRL, FSH, LH, E2, P and T were measured with RIA at the same time. Results: In 3women the acute and heavy bleeding was stopped in 5 days with treatment of LHRH-A and generalantihemorrhagic medicine. In 7 women the irreqular bleeding became reqular and amenorrhea, and in another4 cases the heavy bleeding with regular cycle was decreased significantly and amenorrhea after treatment ofLHRH-A. The serum FSH, LH, E2 and P were suppressed. Conclusion: The effect of LHRH-A in treatmentof abnormal uterine bleeding was satisfactory. Its advantage is that side effects were little and liver functionwas not affected.
出处 《北京医科大学学报》 CSCD 1997年第4期357-359,共3页 Journal of Peking University(Health Sciences)
关键词 子宫出血 药物疗法 LHRH-A Uterine hemorrhage/drug ther LHRH-A Gonadorelin/ther use
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参考文献1

  • 1耿力,中华妇产科杂志,1994年,29卷,592页

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