摘要
目的探讨^125I粒子植入加胆道支架治疗中晚期高位胆管癌的方法和效果。方法应用放射性。^125I粒子植入加胆道支架联合治疗14例中晚期高位胆管癌。结果所有患者术后均无异常反应，复查血常规，白细胞及粒细胞无明显下降，无明显放射性损害表现。手术后总胆红素、谷氨酸氨基转移酶、天冬氨酸氨基转移酶、γ-谷氨酰转肽酶、碱性磷酸酶均较术前下降。14例患者随访7～20个月，术后生存7～20个月，平均生存13个月。结论对无法行根治性切除术的中晚期高位胆管癌患者行^125I粒子植入加胆道支架治疗，可有效地解除黄疸，改善肝功能，提高患者的生存质量，延长生存期。
Objective To discuss the clinical method and the effect of advanced hilar cholangiocarcinoma with implantation of permanent ^125iodine （^125I） seeds combined with stent. Method ^125I radioactive seeds combined with stent were applied to treat 14 patients with advanced hilar cholangiocarcinoma. Results All operations were performed successfully. There were no paradoxical reaction postoperatively. The total bilirubin, alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transpeptidase and alkaline phosphatase were lower after operation than those before operation. The mean survival time of 14 patients who were foUowed up for 7-26 months was 13 months. Conclusion The use of ^125I radioactive seeds combined with stent could relieve biliary obstruction and improve hepatic function, so it is advocated in the patients with unresectable advanced hilar chohngiocarcinoma.
出处
《中国医师进修杂志（外科版）》
2008年第1期28-30,共3页
Chinese Journal of Postgraduates of Medicine
关键词
胆管肿瘤
碘同位素
支架
Bile duct neoplasms
^125I seeds
Stents
