摘要
目的:研究豨莶草胶囊对麻醉犬脑血流量(CBF)、脑血管阻力(CVR)、血压、心电图及心率的影响。方法:将犬结扎一侧颈外动脉及椎动脉,以电磁流量计测颈动脉血流量,以多道生理记录仪记录血压、心电图及心率的变化。结果:豨莶草胶囊可显著增加麻醉犬的CBF,降低CVR,但对麻醉犬的血压、心电图及心率无显著影响。结论:豨莶草胶囊可通过增加CBF及降低CVR,改善脑血液循环。
OBJECTIVE： To study the effect of Herba Siegesbeckiae capsule on cerebral blood flow （CBF）, cerebral vessel resistance （CVR）, blood pressure （BP）, electrocardiogram （ECG） and heart rate （HR）in anesthetized dogs. METHODS： The external carotid arteries on one side and the vertebral arteries of dogs were ligated, then the CBF of carotid arteries was mea- sured by electromagnetic flowmeter, and the BP, EGG and HR were measured by polygraph. RESULTS： Herba Siegesbeckiae capusle could significantly increase CBF and decrease CVR; however, it has no effect on BP, ECG and HR. CONCLUSION： Herba Siegesbeckiae capsule can improve cerebral blood circulation through increasing CBF and decreasing CVR.
出处
《中国药房》
CAS
CSCD
北大核心
2008年第3期178-180,共3页
China Pharmacy
关键词
豨莶草胶囊
脑血流量
脑血管阻力
实验研究
Herba Siegesbeckiae capsule
Cerebral blood flow
Cerebral vessel resistance
Empirical study
