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脂质乳剂释药机制及其靶向性的研究进展 被引量：12

Progress of Lipid Emulsions on Drug Release Mechanism and Targeting Delivery
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摘要 简要介绍了脂质乳剂释药机制、体内外试验方法及影响释药特性和靶向性的因素,如粒径、药物性质、表面修饰等研究进展。 The drug release mechanism, in vitro and in vivo test methods of lipid emulsions are oneny demonstrated. The study progress of influence factors such as diameters, characteristics of drug and surface modification of lipid emulsions on drug release and targeting delivery is reviewed.
作者 何军 张兵 陈艳华
机构地区 上海医药工业研究院 茂祥集团(长春)制药有限公司
出处 《中国医药工业杂志》 CAS CSCD 北大核心 2008年第1期56-60,共5页 Chinese Journal of Pharmaceuticals
关键词 脂质乳剂 释药机制 靶向给药 综述 lipid emulsions drug release mechanism targeting delivery review
分类号 R944.9 [医药卫生—药剂学]
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参考文献26

  • 1Seki J, Sonoke S, Saheki A, et al. A nanometer lipid emulsion, lipid nano-sphere (LNS), as a parenteral drug carrier for passive drug targeting [J]. Int J Pharm, 2004, 273 (1-2) : 75-83.
  • 2林巧平,周建平.药物载体脂肪乳的研究与应用[J].药学进展,2005,29(8):359-364. 被引量：13
  • 3Kawakami S, Yamashita F, Hashida M. Disposition characteristics of emulsions and incorporated drugs after systemic or local injection EJ]. Adv Drug Deliv Rev, 2000, 45(1) : 77-88.
  • 4Hosokawa T, Yamauchi M, Yamamoto Y, et al. Evaluation of the carrier potential for the lipid dispersion system with lipophilic compound[J]. Biol Pharm Bull, 2003, 26 (7): 994-999.
  • 5Hosokawa T, Yamauchi M, Yamamoto Y, et al. Role of the lipid emulsion on an injectable formulation of lipophilic KW-3902, a newly synthesized adenosine Al-receptor antagonist [J]. Biol Pharm Bull, 2002, 25 (4) : 492-498.
  • 6Hosokawa T, Yamauchi M, Yamamoto Y, et al. Formulation development of a filter-sterilizable lipid emulsion for lipophilic KW-3902, a newly synthesized adenosine Alreceptor antagonist [J]. Chem Pharm Bull (Tokyo), 2002,50 (1): 87-91.
  • 7瞿文,陈庆华,朱宝泉.脂质纳米球的研究进展[J].中国药学杂志,2001,36(11):724-728. 被引量：10
  • 8高晓黎,孙殿甲,程利勇,毕殿州.去氢骆驼蓬碱注射用乳剂中药物的相分布和体外释放研究[J].中成药,2000,22(2):111-115. 被引量：11
  • 9Magalhaes NS, Fessi H, Puisieux F, et al. An in vitro release kinetic examination and comparative evaluation between submicron emulsion and polylactic acid nanocapsules of clofibride [J]. JMicroencapsul, 1995, 12 (2) : 195-205.
  • 10Wang JJ, Sung KC, Hu OY, et al. Submicron lipid emulsion as a drug delivery system for nalbuphine and its prodrugs [J]. J Controlled Release, 2006, 115 (2) : 140-149.

二级参考文献67

  • 1王鸿,杨纲,梁文权.盐酸布比卡因冻干乳剂的制备[J].海峡药学,2004,16(4):21-22. 被引量：7
  • 2[1]Singh M,et al.J Parenter Sci Technol[J].1986,40:34.
  • 3[2]Shinanoto Tsugio,et al.Chem Pharm Bull[J].1973,21(2):316.
  • 4[3]Teagarden DL,et al.J Pharm Res[J].1988,5:482.
  • 5[4]Washington C.Int J Pharm[J].1990,58:1.
  • 6[5]Levy MY,et al.Int J Pharm[J].1990,66:29.
  • 7Anderson C, Anderson T, Molander M. Ethanol absorption across human skin measured by in vivo microdialysis technique [J]. Acta Derm Venereol, 1991,71(3):389-393.
  • 8Ault JM, Lunte CE, Meltzer NM, et al. Microdialysis sampling for the investigation of dermal transport [J]. Pharm Res, 1992,9(10):1256-1261.
  • 9Ault JM, Riley CM, Meltzer NM, et al. Dermal microdialysis sampling in vivo [J]. Pharm Res, 1994,11(11):1631-1639.
  • 10Hsiao JK, Ball BA, Morrison PF, et al. Effects of different semipermeable membranes on in vitro performance of microdialysis probes [J]. J Neurochem, 1990,54(10):1449-1506.

共引文献46

同被引文献123

引证文献12

二级引证文献51

中国医药工业杂志
2008年 第1期

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